The Course of Renal Function After Radical Cystectomy with Ileal Conduit Diversion for Bladder Cancer
Journal Title: JOURNAL OF UROLOGICAL SURGERY - Year 2019, Vol 6, Issue 1
Abstract
Objective: We evaluated the course of the renal function and potential risk factors for renal deterioration in patients who had undergone radical cystectomy with ileal conduit diversion. Materials and Methods: A retrospective study evaluated 121 patients, including 114 male and 7 female who underwent radical cystectomy with ileal conduit diversion. Estimated glomerular filtration rate (eGFR) was calculated and postoperative changes in renal function were reviewed. The clinical variables influencing renal function were evaluated. Results: The median follow-up period was 35.6 months (range, 12.2 to 139.6 months). The mean eGFR was 78.37±27.58 mL/min/1.73 m2 before surgery and 90.14±29.68 mL/min/1.73 m2 at 5 years postoperatively. The comparison of preoperative eGFR and the last follow-up eGFR showed the no statistically significant difference (p=0.195). Statistical analysis showed that development of postoperative urinary tract obstruction and postoperative urinary tract infection were significant adverse factors (p=0.008, p=0.026, respectively). Conclusion: Thirty two patients (53.3%) developed renal deterioration during the follow-up period. Development of urinary tract obstruction and urinary tract infection in the postoperative period were found to be significant adverse factors affecting renal function.
Authors and Affiliations
Cevahir Özer, Mehmet Reşit Gören, Tulga Eğilmez, Ferhat Kılınç, Sezgin Güvel
Effect of Temperature and Humidity on Serum Prostate Specific Antigen Levels in Asymptomatic Male Population
Objective To determine the possible effect of climate parameters on prostate specific anigen (PSA) levels. Materials and Methods Among 2.150 males, 757 individuals participating in a general check-up service at our hospi...
Local Anesthetic Infiltration During Pediatric Percutaneous Nephrolithotomy Improves Postoperative Analgesia
Objective: Percutaneous nephrolithotomy is not pain-free due to the procedure itself and presence of post-operative diversion. Our purpose was to evaluate the efficacy of local anesthetic infiltration in postoperative an...
Effects of Treatment on Angiogenic (Vascular Endothelial Growth Factor-2 and Matrix Metalloproteinase-2) and Antiangiogenic (Endostatin and Thrombospondin-1) Factors in Non-muscle Invasive Bladder Carcinoma
Objective: We aimed to investigate possible effects of treatment on angiogenic [vascular endothelial growth factor-2 (VEGF-2) and matrix metalloproteinase-2 (MMP-2)] and antiangiogenic [endostatin (ES) and thrombospondin...
MiT Family Translocation Renal Cell Carcinomas
.
Prevalence of Anal Incontinence and Constipation in Female Patients with Urinary Incontinence
Objective: To investigate the prevalence of anal incontinence and constipation in patients with urinary incontinence. Materials and Methods: Adult female patients who presented with the complaint of urinary incontinence...