The Current Research Progress of Recanalisation and Reperfusion Therapies of Acute Ischemic Stroke
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 9
Abstract
Stroke (cerebrovascular accident) is characterised by the sudden loss of blood circulation to a region of the brain, which results in loss of neurological capacity. Strokes are delegated either hemorrhagic or ischemic. As in acute ischemic stroke, it is caused by thrombosis or embolism, which is more typical than hemorrhagic stroke. Blood flow restoration can moderate the ischemia impacts if performed quickly. In the most recent decades, thrombolysis has had the crucial role of catalysing and driving all the advancements; in this way, changes occurred in the management of acute ischemic stroke. The rationale for the utilisation of systemic or local thrombolytic agents or other endovascular methods is the lysis or expulsion of the disturbance of thrombus or emboli occluding brain vessels. Recanalisation procedures, which incorporate intravenous (IV) recombinant tissue-type plasminogen activator (rt-PA), and intra-arterial approaches, endeavour to establish revascularisation so that irreversible damage can be prevented from happening. This review article will focus on the current research progress of recanalisation and reperfusion therapies of acute ischemic stroke.
Authors and Affiliations
Md Rezaul Karim
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