The Diagnosis of posterior Reversible Leukoencephalopathy Syndrome: A Prospective Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Introduction Reversible posterior leukoencephalopathy syndrome (PRES) is a reversible condition with vasogenic cerebral edema as amain pathological feature. Lesion mainly involves posterior part of cerebrum with wide range ofsymptoms ranging from headache,seizure,altered mental status, nausea, vision loss etc. Aim To study the clinical and radiological features of PRES. Material And Methods A prospective study was conducted in Mahatma Gandhi Medical College,Jaipur with 15 cases from June 2017- December 2017. Results Out of 15 patients, 12 were female and 3 were male with a mean age of 32.06 years. Most common presentation was seizure(53.3%) followed by altered mental status (33.3%) and headache (13.3%). Main comorbid illness in our study were eclampsia and postpartum sepsis (46.6%), renal diseases (26.6%),hypertension (26.6%). Most common site was occipito-parietal region on MRI brain (86.6%). Other atypical presentation involved temporal lobe (40%), basal ganglia (20%) and infarct (13.3%). Conclusion PRES is a reversible condition and has good outcome in most of the patients. In our study seizure is the most common presentation and hypertension is the most common comorbid illness and occipital regions are most common site on MRI.
Authors and Affiliations
Dr PareshKumar Sukhani, Dr Nipun Gumber, Dr Hemant Kumar Mishra
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