THE DIAGNOSTIC VALUE OF “CENTOR CRITERIA” IN CHILDREN WITH GROUP A BETA HEMOLYTIC STREPTOCOCCUS TONSILLOPHARYNGITIS
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2018, Vol 5, Issue 8
Abstract
Background: Centor criteria (fever >38.5°C, swollen, tender anterior cervical lymph nodes, tonsillar exudate and absence of cough) include a scoring system used to assess the probability of group A β hemolytic Streptococcus (GABHS) as the origin of sore throat, and it is developed for adults. Up till now, there’s no graded scoring system established for children with suspected GABHS pharyngitis. Thus, it is important to evaluate the correlation between Centor criteria and presence of GABHS in children with sore throat. Objectives: This study was intended to test the Centor Criteria as a scoring system for GABHS in children and assess its diagnostic value to guide us toward whether to perform to a rapid diagnostic point of care (POC) test/throat culture in pediatric patients presenting with sore throat. In addition to assessing the impact of this scoring system with the support of practical laboratory tests: the WBC and the CRP. Methods: We proposed to carry out a retrospective cross-sectional study at the Makassed General Hospital in children (aged 3–15 years) diagnosed with tonsillitis. We recorded Centor scoring in addition to white blood cell count (WBC), C-reactive protein (CRP), rapid antigen detecting test and throat culture. Results: 484 children with tonsillitis were enrolled between 1st January 2010 and 31st July 2017. GAS was positive in 129 (26%) cases and negative in 358 (74%). In GAS cases, two of the Centor criteria were observed to be positive in 4 (3.1%), while 122 (94.6%) cases met three to four Centor criteria with a significant p-value (<0.001).The specificity of having three/four criteria was found to be 62 % and increased to 97% after including CRP and WBC. Conclusion: Centor criteria could be a tool to be used to reduce unnecessary rapid diagnostic point of care (POC) test/throat culture in children presenting with sore throat.
Authors and Affiliations
Dr. Mona Orra
Keywords
Related Articles
- EP ID EP637218
- DOI -
- Views 164
- Downloads 0
AICARDI SYNDROME: CASE REPORT
Aicardi syndrome is a congenital disorder characterized by severe psychomotor retardation, corpus callosum agenesis, chorioretinal lacunae, and early-onset infantile spasms. The prognosis is generally poor for children w...
REVIEW OF SPINDLE CELL LESIONS OF THE ORAL CAVITY PART II
Spindle cell lesions are lesions that consist of spindle-shaped cells in the histopathology. Due to complex nature of the oral cavity, presence of neural tissue, and varied type of lesions occurring in oral cavity, Spind...
ANALYSIS OF GENOTOXICITY OF CEFTRIAXONE IN HUMAN LYMPHOCYTE CULTURES
Introduction: Genotoxic effect of ceftriaxone, a antibiotic of the third generation cephalosporins, have been evaluated. Metods: In vitro analysis included evaluation of the genotoxic and cytotoxic potential of different...
WOMEN REPRODUCTIVE HEALTH CARE IN WEST GODAVARI DISTRICT OF ANDHRA PRADESH (A MICRO LEVEL ANALYSIS OF CHINTALAPUDI MANDAL)
In this paper an attempt is made to sketch the Status of Reproductive Health of Women in West Godavari District of Andhra Pradesh. The study is based on primary data. For this purpose 100 sample women respondents are sel...
NUTRITION TO COMBAT DIABETES-AYURVEDIC PERSPECTIVE
Nutrition is of paramount importance in the management and prevention of type 2 Diabetes. Urgent solutions for slowing, or even reversing, this trend are needed, especially from investment in modifiable factors including...