The Effect of a Period of Swimming Training and Chamomile Extract on Antioxidant Status in Adult Male Rats
Journal Title: مجله علمی- پژوهشی دانشگاه علوم پزشکی قم - Year 2018, Vol 12, Issue 6
Abstract
Background and Objectives: Exercises lead to increased free radicals. However, medicinal plants can prevent oxidative stress and cellular damage through their antioxidant effect. Therefore, in this study, the antioxidant effects of swimming training and chamomile extract, was investigated in adult male rats. Methods: In this experimental research, 35 Sprague-Dawley male rats, were selected and divided into 5 groups of 7 rats, including (1) control, (2) swimming training, (3) chamomile extract, (4) swimming training and chamomile extract, and (5) sham groups. Groups 2 and 4 performed forced swimming for 8 weeks (three 60-minute sessions per week), and groups 3 and 4 peritoneally received chamomile extract (200mg/kg) for 8 weeks. Serum levels of the variables, were evaluated using spectrophotometric method. Statistical analysis of data, was performed using Kolmogorov–Smirnov, one-way ANOVA, and Tukey post hoc tests (p≤0.05). Results: In this study, swimming training, chamomile consumption, and swimming training with chamomile consumption have a significant effect on the increase of total antioxidant capacity in the rats (p=0.001). Moreover, chamomile consumption (p=0.004), swimming training (p=0.001), and swimming training with chamomile consumption (p=0.001) had a significant effect on decreased levels of malondialdehyde in rats, and consumption of chamomile (p=0.04), swimming training (p=0.01), and swimming training with chamomile consumption (p=0.03) had significant effect on increase in glutathione level in rats. Conclusion: According to the findings, it seems that swimming training, chamomile consumption, and their combination, can be used to improve the antioxidant status.
Authors and Affiliations
Fereshteh Mohammad Hosseini, Seyed Ali Hosseini, Mozhgan Ahmadi
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