THE EFFECT OF DEXAMETHASONE ON POST-OPERATIVE NAUSEA AND VOMITING IN PATIENTS WHO UNDERWENT TONSILLITIS SURGERY AT THE ADESH INSTITUTE OF MEDICAL SCIENCE AND RESEARCH UNIVERSITY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 35
Abstract
PONV occurs frequently after day case tonsillectomy surgery both 5-HT3 antagonists and dexamethasone are superior to placebo in the prophylaxis of PONV in his setting. Our study has compared the efficacy of ondansetron plus dexamethasone with each anti-emetic alone for the prevention of PONV in patients undergoing day case tonsillectomy surgery. Present study was undertaken on 279 patients in the age group of 10-38yrs. Group 1 received Inj. Dexamethasone 8mg as single dose I V bolus 5 minutes before induction of anaesthesia. Group 2 received Inj. Ondansetron 4mg as single dose I V bolus 5 minutes before induction of anaesthesia. Group 3 received Inj. Ondansetron 4mg with Inj. Dexamethasone 8mg as single dose I V bolus 5 minutes before induction of anaesthesia A standard anaesthetic protocol was used in all the patients. As per our observations, the incidence of PONV in 0 – 4 hours postoperative period was statistically significant. The observations were inconclusive beyond the 4 hour period in combination group as well as either drug group. Combination of Inj. Ondansetron 4mg with Inj. Dexamethasone 8mg proved to be more efficacious over either drug alone.
Authors and Affiliations
Grace Budhiraja, Monika Gupta, Paramdeep Singh
Keywords
Related Articles
- EP ID EP231807
- DOI 10.18410/jebmh/2015/746
- Views 64
- Downloads 0
AWARENESS AND KNOWLEDGE OF DIABETIC EYE DISEASE AMONG DIABETIC PATIENTS PRESENTING TO EYE OPD IN CENTRAL INDIA
BACKGROUND Diabetic eye disease can lead to permanent visual impairment or blindness if medical attention is delayed. Awareness and knowledge of diabetes-related eye complications is important for early medical presentat...
SERUM HOMOCYSTEINE AS A RISK FACTOR IN ISCHAEMIC STROKE- A CROSS-SECTIONAL OBSERVATIONAL STUDY IN A TERTIARY CARE TEACHING HOSPITAL IN NORTHERN KERALA
BACKGROUND Stroke is a clinically-defined syndrome of rapidly developing symptoms or signs of focal loss of cerebral function with no apparent cause other than that of vascular origin. A previously unrecognised risk fact...
VITAMIN D LEVELS AND ITS RELATIONSHIP WITH BONE MINERAL DENSITY AMONG POSTMENOPAUSAL WOMEN IN CENTRAL INDIA
BACKGROUND To determine vitamin D (25OHD) status and its relationship with bone mineral density (BMD) in 100 postmenopausal women. MATERIALS AND METHODS Postmenopausal women were included according to inclusion and exclu...
CLINICAL, NEUROPSYCHOLOGICAL AND NEUROPHYSIOLOGICAL CORRELATES OF DRUG RESISTANT JUVENILE MYOCLONIC EPILEPSY
This study was designed to find the clinical, neuropsychologic, EEG and TMS (Transcranial Magnetic Stimulation) characteristics of patients with treatment resistant Juvenile Myoclonic Epilepsy (JME). JME diagnosis was ac...
MYCOLOGICAL STUDY OF ASPERGILLUS INFECTIONS IN KERATOMYCOSIS
In recent years, fungi have been emerging more commonly as infectious agents in patients of tertiary care centers. AIM: The present study was undertaken to find out the prevalence of aspergillus infection causing keratom...