The Effect of Exercise on Serum Homocysteine, Adma, Neopterin and Oxidative Stress Levels in Young Male Athletes
Journal Title: International Journal of Applied Exercise Physiology - Year 2018, Vol 7, Issue 4
Abstract
Elevated homocysteine (HCY), asymmetric dimethylarginine (ADMA), Neopterin (NP) and oxidative stress have been established as risk factors for vascular disease and coronary artery disease. The purpose of the study was (a) to assess the HCY, ADMA, NP, malondialdehyde (MDA) and glutathione (GSH) levels and (b) to determine the relationship between these parameters in wrestlers, track and field athletes, and non-athletes. 35 subjects in total, comp i ing of 15 w e le x 17.6 ± 2.3 yea ), 10 track and field athletes x 16.6 ± 2.2 yea ) and 10 non-a hle e x 17.2 ± 0.8 yea ) volun a ily pa icipa ed in he udy. The HCY, ADMA, NP, MDA, GSH levels as in subjects' blood was performed through the antecubital vein in the morning while in the pre-prandial state. There was a significant difference in ADMA, MDA, GSH concentrations between in track and field athletes and wrestlers. There was a significant difference in HCY, NP concentrations between wrestlers and non-athletes. There was a significant difference in HCY, MDA concentrations between track and field athletes and non-athletes (p< 0.05). The HCY and NP showed high level correlation in all groups (track and field athletes; r = .952; wrestlers; r = .886; non-athletes; r = .900; p< 0.01). The GSH and NP showed high level negative correlation in non-athletes (r = - .900; p< 0.01). According to the results of HCY, ADMA, NP, MDA, the lowest level was found in athletes and the highest appeared in the non-athletes. In conclusion, we think that regular training may have positive effects on cardiovascular and anti antioxidant level.
Authors and Affiliations
Sema Can, Erkan Demirkan, Emre Avcı
Keywords
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- EP ID EP571992
- DOI 10.30472/ijaep.v7i4.290
- Views 82
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