The effect of fluticasone furoate nasal spray on the intraocular pressure in patients of allergic rhinitis: A cross sectional study from eastern India
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 2
Abstract
Background Rhinoconjunctivitis is a common health problem that plagues the lives of children and adolescents alike with a significant impairment of the quality of lifePurpose Aim of this study was to investigate the effect of intranasal corticosteroid fluticasone furoate on the change of IOP in allergic rhinitis patientsMaterials and Methods This was a prospective observational study carried at the Ophthalmology outpatient department of a Government Medical College in West Bengal involving all consecutive patients attending ENT OPD for allergic rhinitis of age group 12 years and above and prescribed fluticasone furoate nasal spray The IOP of patients were measured before and after start of steroid nasal spray and follow up was done at regular interval One and half year and follow up was done on 1st 2nd 4th 8th and 12th week respectivelyResults A total of 108 patients were selected for the study out of which 100 remained till the end of all follow ups The IOP for each eye was compared with baseline IOP values RE 1602229 LE 1604220 and at the end of the study the P value for each follow up was calculated The t test revealed that there was no significant change increasedecrease in IOP in any eye over the course of time r values shows that there was a strong positive linear correlation of IOP between and within the eyes at different levels of assessment after the starting of the treatment Even after age group adjustment there was no statistical difference in IOP between the eyes among the various age groupsConclusion The study demonstrates no statistically significant increase in IOP after the administration of fluticasone furoate nasal spray We believe therefore that fluticasone furoate administered for a short time for the treatment of nasal allergy is safe in terms of its effect on IOP in the Indian populationKeywords Allergic rhinoconjunctivitis Fluticasone furoate Intranasal steroids Steroid induced glaucoma
Authors and Affiliations
Smaranjit Biswas, Shashwat Bhattacharyya, Kanchan Kumar Mandal, Biswarup Ray
Ocular manifestations of rheumatic diseases: A hospital based study
Abstract Background: Changes in the organ of sight in rheumatic diseases may result from the inflammatory process because of immune-mediated ocular inflammation which causes severe debilitation and visual loss. Therefore...
A study of prevalence of dry eye in relation to trachoma
Introduction: Dry eye disease is a multifactorial disorder of the tear film due to tear deficiency or excessive tear evaporation, which causes damage to the ocular surface leading to tear film instability and is associat...
A clinical study of the pre-corneal tear film in diabetic and non-diabetic persons- a case control study
Introduction Several local and systemic disorders predispose to the development of dry eye disease common among them being diabetes mellitus This study aims to assess the incidence of dry eye in diabetics and analyse the...
Vitamin A deficiency in chronic kidney disease patients attending a tertiary care hospital
Background: Patients with Chronic kidney Disease are at the risk of developing a deficiency or excess of one or more micronutrients because of inadequate intake, interference of micronutrient absorption either by drug or...
Inter ocular variability of common glaucoma parameters in patients with primary open angle glaucoma
Aim: To assess the intrasubject variability of CCT,IOP and VCDR in patients with POAG compared to normal. Design: Cross sectional study. Materials and Methods: A total of 100 eyes of patients on treatment for POAG and 10...