The effect of fluticasone furoate nasal spray on the intraocular pressure in patients of allergic rhinitis: A cross sectional study from eastern India
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 2
Abstract
Background Rhinoconjunctivitis is a common health problem that plagues the lives of children and adolescents alike with a significant impairment of the quality of lifePurpose Aim of this study was to investigate the effect of intranasal corticosteroid fluticasone furoate on the change of IOP in allergic rhinitis patientsMaterials and Methods This was a prospective observational study carried at the Ophthalmology outpatient department of a Government Medical College in West Bengal involving all consecutive patients attending ENT OPD for allergic rhinitis of age group 12 years and above and prescribed fluticasone furoate nasal spray The IOP of patients were measured before and after start of steroid nasal spray and follow up was done at regular interval One and half year and follow up was done on 1st 2nd 4th 8th and 12th week respectivelyResults A total of 108 patients were selected for the study out of which 100 remained till the end of all follow ups The IOP for each eye was compared with baseline IOP values RE 1602229 LE 1604220 and at the end of the study the P value for each follow up was calculated The t test revealed that there was no significant change increasedecrease in IOP in any eye over the course of time r values shows that there was a strong positive linear correlation of IOP between and within the eyes at different levels of assessment after the starting of the treatment Even after age group adjustment there was no statistical difference in IOP between the eyes among the various age groupsConclusion The study demonstrates no statistically significant increase in IOP after the administration of fluticasone furoate nasal spray We believe therefore that fluticasone furoate administered for a short time for the treatment of nasal allergy is safe in terms of its effect on IOP in the Indian populationKeywords Allergic rhinoconjunctivitis Fluticasone furoate Intranasal steroids Steroid induced glaucoma
Authors and Affiliations
Smaranjit Biswas, Shashwat Bhattacharyya, Kanchan Kumar Mandal, Biswarup Ray
Keywords
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- EP ID EP474219
- DOI 10.18231/2395-1451.2018.0051
- Views 71
- Downloads 0
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