Abstract

Background: The word “garlic” comes from old English garleac, meaning “spearleek”. It consists of numerous “bulb lets” or individual cloves grouped together and enclosed in a thin white skin. It is scientifically known as Allium sativum and belongs to the family liliacese (liliiocese). The study was aimed at investigating the efficacy of garlic extracts on the blood sugar level of wistar albino rats. The aim of this experiment was to study the efficacy of garlic extracts on the blood sugar level of wistar albino rats. Materials & Methods: Twentyeight albino wistar rats were used for this investigation to determine the efficacy of an aqueous extract of raw garlic in controlling blood-sugar level. The raw extract of garlic (Allium sativum) was administered daily to the rats orally for 28days. The rats weighed between 200- 375g.The serum levels of glucose were measured. Results & Discussions: When the rats were treated with a low dose (10% and 50%) of raw aqueous extract of garlic, no significant changes in the serum glucose levels were observed compared with the control group. When the rats were treated with the raw garlic, glucose levels were significantly affected (Like a case that dropped from 102mg/dl to 75mg/dl resulting in hypoglycaemia). Raw garlic had a profound effect of reducing the glucose level in the blood and also led to marked weight loss (in one case, from 175g to 150g) as well as appreciable hair loss. Conclusion: Raw garlic extract apart from reducing blood-sugar level and inducing weight loss in rats.

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