The Effect of Green Tea Leaf Extract on Reproductive Function of Male Wistar Rats
Journal Title: International Journal of Trend in Scientific Research and Development - Year 2021, Vol 5, Issue 4
Abstract
This study assessed the effects green leaf tea extract on male reproductive function of male albino wistar rats. Twenty rats weighing between 150 250g, grouped into 4 of 5 rats each, were used for the research that lasted for four weeks. Group I, the control group, received normal rat chow and water ad libitum. The three test groups II IV, received 2.5gm 100ml 0f water, 5gm 100ml of water, 7.5gm 100ml of water of green leaf tea extract given via oral administration with normal rat food and water for four weeks. Blood was collected via ocular puncture and serum was assayed for testosterone levels. Semen was also analyzed for sperm motility and sperm count. The testicular weight was recorded and net body weight gain was also recorded. The study showed significant decrease in net body weight gain and testicular weight. It has been shown that the reduction of body weight after application of green tea extract may be due to inhibition of catechol O methyl transferase transferase COMT enzyme by epigallocatechin gallate EGCG of the green tea. The study also showed significant decrease in sperm motility and sperm count. It also showed a significant decrease in testosterone levels. In conclusion, green leaf tea extract had a negative effect on male reproductive function and its use as a daily tea should be curtailed. Okonkwo, C. O. J | Maduka, S. O | Akude Harrison | Mmaju, C. I | Okwuonu, I. F1; Goji A. D "The Effect of Green Tea Leaf Extract on Reproductive Function of Male Wistar Rats" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-4 , June 2021, URL: https://www.ijtsrd.compapers/ijtsrd42471.pdf Paper URL: https://www.ijtsrd.commedicine/other/42471/the-effect-of-green-tea-leaf-extract-on-reproductive-function-of-male-wistar-rats/okonkwo-c-o-j
Authors and Affiliations
Okonkwo, C. O. J | Maduka, S. O | Akude Harrison | Mmaju, C. I | Okwuonu, I. F1; Goji A. D
Keywords
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