The Effect of Hydroxyurea in Sickle Cell Disease Patients
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 4
Abstract
Aim: To know the effect of hydroxyurea in sickle cell disease patients by measuring the HbF levels. Materials and Methods: 50 patients suffering from sickle cell disease were taken from Prince Saud Bin Jalavy Hospital, Alahsa. The HbF levels were monitored in these patients before and after 4 months of administration of hydroxyurea. The HbF were monitored using Hb Electrophoresis. Observation: The mean difference was – 0.3979 with SD of 0.0663, standard error 0.0094 and t value 0f-42.32 and p value of p<0.0001 Conclusion: In all patients there was 20-25% of improvement of fetal Hb after 4 months of treatment with hydroxyurea.
Authors and Affiliations
Dr. Spvittal, Dr. Mir Firman Ali, Dr. C. Ramakrishna, Mr. B. Venkateswar Rao
Keywords
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- EP ID EP594967
- DOI 10.9790/0853-160407113116.
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