The effect of ketamine on the lipopolysaccharide-induced inflmmation in in vitro culture of HUVEC
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2015, Vol 5, Issue 11
Abstract
Objective: To report the effect of ketamine treatment on inflammatory cytokines induced by lipopolysaccharide. Methods: Human umbilical vein endothelial cells culture was used in this research. The measurement of inflammatory cytokines was performed by using ELISA. Results: The results showed various levels of inflammatory cytokines. The nuclear factor-κB results were unstable, but interleukin 6 and tumor necrosis factor-α showed similar results. The expressions of interleukin 6 and tumor necrosis factor-α decreased in all observation times. Conclusions: In general, our results of human umbilical vein endothelial cells culture were supported by other researches related with the effect of ketamine in suppressing inflammatory effect induced by lipopolysaccharide. Ketamine could suppress inflammatory cytokines in all observation times.
Authors and Affiliations
Keywords
Related Articles
- EP ID EP228416
- DOI 10.1016/S2222-1808(15)60952-5
- Views 100
- Downloads 0
Assessment of hepatitis B virus and hepatitis C virus infections and associated risk factors in HIV infected patients at Debretabor hospital, South Gondar, Northwest Ethiopia
Objective: To assess hepatitis B and hepatitis C virus infections and associated risk factors among HIV infected patients at Debretabor hospital. Methods: A cross-sectional study was conducted among HIV/AIDS patients att...
Effect of seed kernel aqueous extract from Annona squamosa against three mosquito vectors and its impact on non-target aquatic organisms
Objective: To evaluate the toxicity of Annona squamosa (A. squamosa) aqueous (physiological saline) seed soluble extract and its control of mosquito population. Methods: Ovicidal, larvicidal and pupicidal activity of A....
Clerodendron inerme Gaertn. plant as an effective natural product against dengue and filarial vector mosquitoes
Objective: To investigate insecticidal properties of organic solvent extracts of Clerodendron inerme (C. inerme) leaves against larval stages of Aedes aegypti (Ae. aegypti) and Culex quinquefasciatus (Cx. quinquefasciatu...
Monograph: In vitro efficacy of 30 ethnomedicinal plants used by Indian aborigines against 6 multidrug resistant Gram-positive pathogenic bacteria
Objective: To monitor in vitro antibacterial activities of leaf extracts of 30 common and noncommon plants used by aborigines in Kalahandi district, Odisha, against 6 clinically isolated multidrug resistant (MDR) Gram-po...
Association of bioluminescent bacteria from blue swimmer crab Portunus pelagicus (Linneaus, 1758)
Objective: To screen the bioluminescent bacteria from Portunus pelagicus (P. pelagicus) at Thondi coast, Palk Strait, Bay of Bengal, India. Methods: Physico-chemical parameter including atmospheric and surfacewater tempe...