The Effect of Manna on Blood Bilirubin Level in Neonates with Hyperbilirubinemia and Identification of Its Constitutes
Journal Title: European Journal of Medicinal Plants - Year 2016, Vol 11, Issue 4
Abstract
Background: Hyperbilirubinemia is the most common problems in 60% of term infants and 80% of preterm infants. In the case of severe indirect hyperbilirubinemia, it can cause neurotoxic disorders, however, the direct hyperbilirubinemia is considered as severe or systemic problems of liver. Phototherapy and in more severe condition the exchange transfusion are the main treatments that can be used to treat infant jaundice. In traditional medicine manna is also used orally to treat jaundice in infants. The aim of this study was to determine the effect of manna on blood bilirubin levels in neonates with hyperbilirubinemia. Materials and Methods: In this clinical-trial study, a total of 124 neonates with non-hemolytic indirect hyperbilirubinemia, were randomly assigned into four groups (three experimental groups and one control group). The experimental groups were: (A) both mother and neonate respectively recipient 30 cc and 1 cc/kg of the 25% manna solution and phototherapy, (B) only mother recipient of the manna and phototherapy and (C) only neonate recipient of the manna and phototherapy. Control group receiving phototherapy with distilled water. Bilirubin levels were measured at the baseline of experiment and then daily during the experimental period. Results: The results showed that the amount of bilirubin and days of hospitalization had no significant difference among different groups (p˃ 0.05) and the administered manna solution at these doses had no effect on neonatal bilirubin. Conclusion: According to the results of the project, the prescribed doses of manna solution had no effect on neonatal bilirubin. Therefore, it must be used cautiously in infants.
Authors and Affiliations
Mohammad Rahimi-Madiseh, Majid Hamidi, Soleiman Kheiry, Abdolreza Rezaeian-Ramesheh, Mahmoud Rafieian-Kopaei
Keywords
Related Articles
- EP ID EP349653
- DOI 10.9734/EJMP/2016/21909
- Views 115
- Downloads 0
Phytochemical and Pharmacological Investigation of Lagenaria siceraria, Cucumis sativus and
Objective: Cucurbitaceae family is major source of medicinal agents since ancient time. Various plants parts of this family have been established for their pharmacological potential. The aim of present study was to inves...
Importance of Alangium salviifolium and Its Pharmacological Update
Plant based traditional and indigenous medicines are used globally for the treatment of various diseases. About 80% of the world population relies on plants and their products for primary health care. The plant Alangium...
Genetic Analysis of the Bletillae Rhizoma and Its Common Adulterants Using Internal Transcribed Spacer 2 Molecular Barcoding
Aim: This study was designed to discriminate Bletillae Rhizoma from its common adulterants: Iris tectorum, Polygonatum odoratum and Polygonatum cyrtonema using molecular barcoding. Place and Duration of Study: Departmen...
Analgesic, Anti-inflammatory and Other Pharmacological Activities of Methanol Extract of Rhododendron campanulatum from Nepal
Aims: Rhododendron campanulatum D. Don is a plant of Ericaceae family that is found at an altitude of 3000-4200 meters. Traditionally, it has been used to cure rheumatism, hemicranias, sciatica and colds. This study aims...
Antibacterial Effects of Camellia sinensis and Achillea millefolium on Several Antibiotic-resistant Bacteria
Background and Objectives: Infectious diseases are among the most known important causes of morbidity and mortality in the world. The ongoing explosion antibiotic-resistant bacteria and side effects of medications, appli...