The effect of oral contraceptives on selected parameters of homeostasis in young women with sudden balance disorders
Journal Title: Otolaryngologia Polska - Year 2013, Vol 67, Issue 1
Abstract
Introduction: The aim of the study was to evaluate the correlation between hormonal contraceptives and sex hormones levels as a possible cause of vertigo related to coagulation disorders and fibrinolyse. Material and methods: The study was conducted on 25 female patients aged 23–39, who were treated at the Department of Otolaryngology and Laryngological Oncology, Medical University of Lodz, due to vertigo. The studied patients were divided into 3 groups: I – 7 women that used hormonal contraceptives; II – 9 women that no used hormonal contraceptives for the last 6 months; III – 9 women who never used contraceptives. The methodology included: an otoneurological and audiological examination, blood tests, levels of fibrinogen, D-dimers, APTT, PT, ALAT, ASPAT and BMI, estradiol and progesterone levels. Results: In 16 out of the 25 patients the obtained results diverged from normal sex hormones concentration in serum. In each studied group the relation between sex hormones concentration in serum and coagulation and fibrinolyse parameters was proved. The correlation between an increased concentration progesterone and D-dimers was found. Conclusions: An increased concentration of estrogens in serum may have an additional negative effect on a possibility of a thromboembolic episode. In the female patients interested in oral contraception, the prophylactic exclusion of risk factors for a thromboembolic disease seems to be vital.
Authors and Affiliations
Joanna Urbaniak, Hanna Zielińska-Bliźniewska, Piotr Pietkiewicz, Jurek Olszewski
Keywords
Related Articles
- EP ID EP52136
- DOI -
- Views 102
- Downloads 0
Ocular vestibular evoked myogenic potentials to air conduction (AC oVEMP): useful in clinical practice?
SUMMARY Cervical vestibular-evoked myogenic potential (cVEMP) and ocular VEMP (oVEMP) stimuli can be used to measure otolith function using air (AC) and bone conducted (BC) stimuli. Cervical VEMPs reflect saccular functi...
Analysis of the changes in the Polish Universal Neonatal Hearing Screening Program over 15 years of activity
Introduction: One of the examples of a nationwide pro-health program in Poland is the Polish Universal Neonatal Hearing Screening Program (PUNHSP). The Program is aimed at early diagnosis and intervention in children wit...
Does smog affect the incidence of exacerbations of chronic laryngitis? Analysis based on the inhabitants of Lesser Poland Voivodeship.
Introduction: Due to dynamic industrialisation smog became a frequent phenomenon in most developing cities. According to the last WHO report from Global Urban Ambient Air Pollution Database, Krakow has been classified in...
Dekompresja oczodołu w przypadku orbitopatii tarczycowej
SUMMARY Thyroid orbitopathy may result in significant proptosis that causes visual lost. Besides pharmacologic and radiotherapeutic procedures surgically de-compression of the orbital skeleton occasionally is managed. We...
Unusual pathology of submandibular gland –Küttner tumor
Küttner tumor (chronic sclerosing sialadenitis ) is a chronic, benign lesion of salivary gland. Its clinical course resamble malignant process. Autors report two typical cases of CSS affecting submandibular gland. We inf...