The Effect of Pepino (Solanum Muricatum Aiton) Extract on Blood Glucose Level in Type 2 Diabetic Rats
Journal Title: International Journal of Science and Healthcare Research - Year 2018, Vol 3, Issue 4
Abstract
Pepino contains of flavonoid and phenol as antioxidant which can reduce blood glucose level. This research was aimed to study the effect of pepino extract on blood glucose level in type 2 diabetic rats. The study was used randomized pre-posttest control group design. The subjects of this study were 20 male wistar rats divided into 4 groups, they are control group, the group of pepino extract dosage 250 mg/kg, Pepino extract dosage 500 mg/kg body weight (BW), and preventive group. Rats were induced diabetes with alloxan. Pepino extract was supplied for 2 weeks. Blood glucose level was evaluated every week. Results showed that pepino extract affect blood glucose level in diabetic rats (p<0.05). Results of analysis showed the significant difference between control group with the groups of pepino extract dosage 250 mg/kg BW and dosage 500 mg/kg BW (p<0.05). Meanwhile, there was no significant difference between pepino extract dosage 250 mg/kg BW at a dose of 500 mg/kg BW (p>0.05). Pepino extract dosage 250 mg/kg BW was found to have the same effectiveness as 500 mg/kg BW dose to decrease blood glucose level.
Authors and Affiliations
Novia Nurul Chaerunnisa
Keywords
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