The effect of periodontal therapy on IL-17 and IL-23 in Gingival Crevicular Fluid (GCF) of patients with severe periodontitis
Journal Title: Caspian Journal of Dental Research - Year 2013, Vol 2, Issue 1
Abstract
Introduction: Cytokines are the important factors in the progression of periodontal diseases. The aim of this study was to find out the effect of the first phase of the periodontal therapy on the amount of existing IL-17 and IL-23 in gingival crevicular fluid in patients with severe periodontitis and in the control group. Methods: In this clinical trial intervention study,after purifying the parts which were under consideration in 22 patients with severe periodontitis, gingival crevicular fluid was gathered using periopaper located within the gingival sulcus, Then, the first phase of periodontal therapy was carried out and sample taking from the same parts was conducted after 4 weeks. The same phase was carried out on 24 healthy patients (control group). All patients were selected from the Department of Periodontology, Tehran Islamic Azad University Dental Branch. Since the data did not have a normal distribution, therefore, nonparametric tests were used for comparing the groups (Mann-Whitney U Test). A p≤0.05 is considered as significant. Results: The results showed that there was a meaningful and significant difference between the IL-17 viscosity before (p<0005) and after (p<005) the therapy and IL-23 viscosity before (p<0001) and after (p<001) the therapy between the two groups. Conclusions: According to the results of the present study, we can conclude that IL-17 and IL-23 have a significant role in the pathogeneses of periodontal disease.
Authors and Affiliations
Marzieh Rohaninasab, Mandana Sattari, Horrieh Abedi, Nafise Zarenejad
Keywords
Related Articles
- EP ID EP177738
- DOI -
- Views 112
- Downloads 0
Evaluation of frictional resistance between monocrystalline (ICE) brakcets and Stainless Steel, Beta TMA and NiTi arch wires
Introduction: When using sliding mechanics for space closure during orthodontic treatment, friction occurs at the bracket-wire interface. The aim of this study was to evaluate the frictional resistance between monocrysta...
A case report of neurofibromatosis
Introduction: Neurofibromatosis is a genetic disease characterized by multifocal benign tumors of peripheral nerves, called neurofibromas, and pigmented spots on the skin which inherited as autosomal-dominant. The most c...
The effect of surface treatment methods of tooth colored Restorations on shear bond strength
Introduction: Due to undeniable effect of surface treatment on restoration bond strength, this study was conducted to measure and compare the shear bond strength of hybrid ionomer and compomer using the three different m...
Evaluation of the general dentists’ problems during and after posterior composite filling in Babol
Introduction: Posterior composites are one of the most popular filling materials. The aim of this study was to evaluate the problems of general dentists during and after posterior composite restorations in city of Babol....
The relationship between obesity and oral health
Introduction: Obesity as a pervasive phenomenon in recent years has the risky consequences on public and oral health and endangers the teeth especially periodontal tissues. This aim of this study was to assess the relati...