The Effect of Red Dragon Fruit Juice (Hylocereus Polyrhizus) on Liver Histopathological Images in Wistar Rats Exposed to Cigarette Smoke
Journal Title: International Journal of Multidisciplinary Research and Analysis - Year 2024, Vol 7, Issue 07
Abstract
Cigarette smoke contains toxic components, carbon monoxide, hydrogen cyanide, carbon dioxide, and tar, which can trigger the formation of ROS (Reactive Oxygen Species) and reduce antioxidant reserves, which impact oxidative stress and are known to cause damage to liver cell membranes. Red dragon fruit (Hylocereus polyrhizus) is a fruit that is rich in antioxidants that inhibit ROS and prevent damage to liver cells by cigarette smoke. This study aims to assess the effect of administering red dragon fruit juice on liver microscopic images in Wistar rats exposed to cigarette smoke. It was an experimental study with a post-test-only control group design. Thirty-five male Wistar rats (Rattus novergicus) were randomized into five groups. Four groups were exposed to cigarette smoke (K-, P1, P2, and P3), and the fifth group was used as a control (K). All the P-groups were given red dragon fruit juice 2 g/2.5 ml, 4 g/2.5 ml, and 8 g/2.5 ml, respectively, for twenty-eight days. On the 29th day, the livers of Wistar rats were taken for preparation and microscopic observation. The research data were analyzed using the Kruskall-Wallis and Mann-Whitney post hoc tests to determine group differences. The average liver cell damage in K, K-, P1, P2, and P3 were 1.23, 2.51, 1.57, 1.51, and 1.43, respectively. There was a significant difference in damage between the K- group and the P1 (p = 0.002), P2 (p = 0.004), and P3 (p = 0.002) groups. The administration of red dragon fruit juice can protect the liver cells of rats exposed to cigarette smoke.
Authors and Affiliations
Nadya Azura, Desy Armalina, Indah Saraswati, Hermawan Istiadi, Lusiana Batubara
Keywords
Related Articles
- EP ID EP740278
- DOI 10.47191/ijmra/v7-i07-20
- Views 47
- Downloads 0
Parental Involvement and Students' Engagement in Modular Learning Environments
Parental involvement in education improves 'scaffolding' for children's growth and is important in learners' cognitive and behavioral development. This study was specifically conducted to investigate parental involvement...
Explorative Correlational Research Between Superstitious-Belief and Ten-Dimensional Personality Traits of Pupil Teacher from West Bengal Perspective
Superstitious-belief has tremendous effects on the advancement and development of society as well as on personal aspects of a person. The light of education not only eradicates superstitious-belief but also influence per...
Evaluation Study of Physical Education Learning in Sports and Health in Special Schools in Yogyakarta
This research aims to find out: (1) Evaluate the context of elementary learning tools at Yogyakarta State SpecialSchools, (2) Evaluate the input of elementary school infrastructure facilities at Yogyakarta State Special...
Giant Floater (Pyganodon Grandis) as Feed Ingredient in Broiler Production
The focus of the research was to determine how giant floater (Pyganodon grandis) worked as a feed ingredient in broiler production. A total of 120 one-day-old Cobbs 500 were reared for 42 days, regardless of sex. The chi...
An Ethnographic Approach on Betawi Culture: The Existence of Busker of Ondel-Ondel from Cultural Perspective
Ondel-ondel is one of the arts in the form of a tall and large giant doll from the Betawi Tribe. Its existence can still be seen in the community, especially in Pondok Aren Village, South Tangerang. In the history of Bet...