The Effect of Sex and Age Differences on Pathology Results in Primary Bladder Cancer Patients
Journal Title: Üroonkoloji Bülteni - Year 2017, Vol 16, Issue 3
Abstract
Objective: Bladder cancer is more frequently seen in males, whereas prognosis is usually worse in female patients. Although many factors affect the prognosis of urothelial carcinoma of bladder have been proposed, the effect of female gender on the prognosis of bladder urothelial carcinoma is controversial. Several factors have been suggested regarding the effect of gender difference on the prognosis of bladder urothelial carcinoma. Materials and Methods: A retrospective study of 589 patients who underwent transurethral resection for the first time between January 2011 and January 2017 with preliminary diagnosis of bladder cancer was performed. Age, sex, tumor stage, histological subtype and tumor grade were evaluated in the study. Results: No significant difference was found between the sexes in terms of tumor stage (p=0.663). The rate of high-grade tumors was 48.6% (n=235) in males and 63% (n=41) in females and statistically significantly higher in females than males (p<0.041). As the age progressed, it was found that tumor stage and extend increased (p<0.0001). Tumor grade and histological subtype were not statistically significant in terms of age groups. Conclusion: In this study, newly diagnosed bladder tumor patients evaluated and revealed more in male gender. Furthermore, when evaluated in terms of age groups, it was shown that the stage and degree of the tumor increased as the age increased.
Authors and Affiliations
Hakan Türk, Sıtkı Ün, Batuhan Ergani
Keywords
Related Articles
- EP ID EP226671
- DOI 10.4274/uob.857
- Views 120
- Downloads 0
Determination of Six Transmembrane Protein of Prostate 2 Gene Expression and Intracellular Localization in Prostate Cancer
Objective In this study, we aimed to determine the relationship between the RNA and protein expression profile of six transmembrane protein of prostate 2 (STAMP2) gene and androgen and the intracellular localization of...
Risk Adaptive Neoadjuvant Chemotherapy in Muscle Invasive Bladder Cancer
Muscle invasive bladder cancer (MIBC) is an aggressive tumor with a high rate of early systemic dissemination. The main treatment for MIBC is still radical cystectomy and lymph node dissection. Survival rates for 5-year...
Risk Factors for Adrenal Invasion in Renal Cell Carcinoma
Objective: In this study, we aimed to describe the risk factors associated with adrenal invasion in patients who were diagnosed with renal cell carcinoma (RCC) after radical nephrectomy and identify which risk factors ar...
Genomic Evaluation of Testicular Germ Cell Tumors and its Role in Treatment Planning
The incidence of testicular germ cell tumors (TGCT) has significantly increased over the last 40 years and continues to increase among the young male population. The geographical differences show that a combination of ge...
Relationship Between Tumor Density in Radical Prostatectomy Material, Preoperative Predictive Factors and Biochemical Recurrence
Objective: In this study, we assessed the relationship between tumor density (tumor volume prostate volume ratio), preoperative predictive factors and biochemical recurrence (BR) in patients who underwent radical retropu...