The effect of silicon compounds on immunophysiological reactivity of rabbits
Journal Title: Біологія тварин - Year 2017, Vol 19, Issue 3
Abstract
The article displays the results of watering different amounts of silicon citrate obtained by nanotechnology and sodium metasilicate during the 52nd–110th days of life on indicators of cellular and humoral immunity of rabbits. The significant difference of phagocytic activity of neutrophils in the blood of rabbits receiving silicon citrate was found. This indicates stimulating effect of the silicon organic compound on nonspecific resistance cell link. Watering silicon citrate to the animals in research groups compared to watering sodium metasilicate and control had more significant effect on content of lysozyme activity and blood serum bactericidal activity as integral factors of nonspecific resistance of humoral type which was affected by the increase (P<0.05–0.01) of their content in blood on the 31st and the 58th day of the research. The use of organic additives in rabbits’ diets had a stimulating effect of their immune system which was indicated by higher (P<0.05–0.01) content of hexoses associated with proteins, sialic acid and ceruloplasmin in blood of animals which were watered silicon citrate during the research while watering the sodium metasilicate in smaller amount helped to increase (P<0.05) the content of hexoses associated with proteins in rabbits’ blood on the first stage of research and to increase the sialic acid on the last stage compared to the control. The addition of silicon citrate to the rations caused the significant increase of immunoglobulin level in rabbits’ blood during the research and the CIC concentration on the first stage of experiment compared to control which indicates the activating effect of silicon citrate on synthesis of some of their classes in the lymphatic system which provides mechanisms for both humoral and cellular immunity.
Authors and Affiliations
А. I. Ivanytska, Ya. V. Lesyk, M. M. Tsap
Keywords
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- EP ID EP267325
- DOI 10.15407/animbiol19.03.042
- Views 126
- Downloads 0
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