The effect of vitamin D supplementation during resistance training on the markers of systemic inflammation in untrained males

Abstract

Background and Aim: Physical activity has a dual effect on inflammation. Different studies have showed very contradictory results. The present study was designed to investigate the effects of vitamin D supplementation during 8 weeks of resistance training (RT) on IL-6, TNF- α and CRP concentrations. Material and Methods: In this semi experimental study 20 healthy, sedentary men were randomly divided into two groups [(RT-Vitamin D, n = 10) and (RT-placebo, n=10)]. In order to determine IL-6, TNF- α and CRP concentrations, fasting venous blood samples were obtained before and after 8 weeks of supplementation. Resistance training (RT) was performed with increasing intensity every other day (3 sessions per week) for 8 weeks. Intensity of RT increased by 5% every week. During 8 weeks, RT-vitamin D group received one dose of vitamin D (50000 IU) every 2 weeks until the end of the training sessions. Results: Statistical analysis revealed significant decrease in the contractions of IL-6 and TNF- alpha in RT-D supplementation group after training compared to the pretest stage (P≥0/05). The same results were also found in RT- placebo group (P≥0/05), while CRP was not affected by RT- Vitamin D (P˃0/05). However, with time, vitamin D alone had a significant effect on TNF-alpha (P≥0/05). Conclusion: Progressive resistance exercise (PRE) can decrease systemic inflammation (SI) indices in the healthy men with normal body fat percentage, although the combination of vitamin D and resistance training can selectively affect systemic inflammation and decrease the levels of these indices.

Authors and Affiliations

PhD H Matinhomaee, MSc M Zobairy, PhD M. A Azarbayjani, PhD K Azizbeigi

Keywords

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  • EP ID EP282233
  • DOI -
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How To Cite

PhD H Matinhomaee, MSc M Zobairy, PhD M. A Azarbayjani, PhD K Azizbeigi (2017). The effect of vitamin D supplementation during resistance training on the markers of systemic inflammation in untrained males. مجله علمي دانشگاه علوم پزشكي كردستان, 21(86), 89-98. https://europub.co.uk/articles/-A-282233