THE EFFECTS OF IBUPROFEN ON MUSCLE PERFORMANCE, WORKLOAD AND PLASMA CREATINE KINASE DURING A STRENGTH TRAINING SESSION
Journal Title: Medicina Sportiva - Year 2012, Vol 16, Issue 1
Abstract
Introduction: Non-steroidal anti-inflammatory drugs are the most often used substances by athletes. Objective: To determine the effect of non-steroidal anti-inflammatory drug ibuprofen administration before a resistance exercise bout in the total training volume performed as well as in the acute plasmatic levels of creatine kinase. Methods: Twelve strength-trained males (22.8 ± 3.2 years) performed a strength training bout twice: taking 1.2 g of ibuprofen and placebo one hour before the exercise session. Blood levels of creatine kinase (CK) were measured at four times: before (CKpre), immediately after (CK post), and 24h (CK24) and 48h (CK48) after the strength training sessions. In addition, the total volume performed was evaluated to verify possible differences in the training performance. Results: There was no significant difference between the use of ibuprofen or placebo in total strength training volume. Furthermore, no differences were observed between ibuprofen or placebo condition in the CKpre (18.7 ± 8.6 vs. 15.3 ± 3.5), CK post (37.9 ± 19.6 vs. 32.1 ± 16.7), CK24 (16.4 ± 6.4 vs. 16.9 ± 7.0) and CK48 (12.8 ± 4.5 vs. 12.0 ± 5.0) (P>0.05). There was a significant increase in the CK immediately after (CKpost), as well 48 hours after (CK48) in both exercise conditions (placebo and ibuprofen) (P=0.002). Conclusions: The use of ibuprofen does not affect the total strength training volume in a single exercise bout, as well as has no effect in the acute CK responses to this exercise bout.
Authors and Affiliations
Cleiton Correa, Eduardo Cadore, Jocelito Bijoldo, Ronei Pinto, Álvaro de Oliveira, Luiz Fernando Kruel
Keywords
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