The Effects of Kaempferia Galanga L. Extract on Pain, Stiffness and Functional Physic in Patient with Knee Osteoarthritis: Double Blind Randomized Clinical Trial
Journal Title: International Journal of Science and Healthcare Research - Year 2017, Vol 2, Issue 4
Abstract
Background: Osteoarthritis (OA) is a common disease of arthritis and one of the leading causes of disability in aged population specially on knee OA. Objectives: This study was to determine the effect of Kaempferia galanga L. extracts in pain, stiffness, and functional improvement in patient with knee osteoarthritis (OA). Materials and Methods: This study was Double Blind Randomized Clinical Trial. Fourty (40) patients with primary knee OA based symptom and radiographic (K-L grading OA) diagnoses in Tamalanrea public health center, Makassar. Sample is divided into two group, the intervention group by giving Kaempferia galanga L. 160 mg/day and control group by giving meloxicam 15mg/day for 10 days. Outcomes measures using Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) with a visual analog scale (0-10cm) for pain, stiffness, and physical function. Result: The study found out, from 40 samples, 5 were dropped out and 35 samples completed the study (18 intervention and 17 control group). Both groups at the baseline did not show any differences. At the end of the study, there was a significant reduction both intervention and control group for the three WOMAC indicators (pain, stiffness and physical function) with p <0.05 and their reduction did not differ significantly for both groups. Conclusion: Kaempferia galanga L. extract has the same effectiveness as meloxicam for the treatment of knee Osteoarthitis. Therefore, Kaempferia galanga L. as herbal medicine can be used for treatment for Osteoarthritis.
Authors and Affiliations
Akmal Novrian Syahruddin
Keywords
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