The effects of menopausal uterine fibroids on the prognosis of endometrium cancer
Journal Title: Turkish Journal of Obstetrics and Gynecology - Year 2020, Vol 17, Issue 2
Abstract
Objective: This study aimed to evaluate any potential associations between uterine leiomyomas and endometrial cancer. Materials and Methods: This is a retrospective study of 153 female patients who have been operated because of endometrial carcinoma in our hospital between 2012 and 2017. Data were collected from hospital records. Study participants were divided into two groups according to the presence and absence of leiomyomas. These two groups were compared in terms of histopathological adenocarcinoma type, nuclear and histological grades, disease stage, para-aortic lymph node involvement, and myometrial invasion. For data analysis, Statistical Package for Social Sciences 15.0 software package was used. Comparison between the two groups was made using the chi-square test, and each variable was tested with the Student’s t-test for statistical significance. Results: No statistically significant differences were found between the groups with respect to age, tumor type, myometrial invasion, nuclear grade, or histological grade (p>0.05 for all). A significant difference was found between leiomyomas presence and lymph node metastases. The lymph node metastases were more common in patients without uterine leiomyomas (20.55%) than in those with them (5%; p=0.004). Analysis using the Federation of Obstetrics and Gynecology stages for the presence of leiomyomas indicated that the mean stages were 1A and 1B in patients with and without uterine leiomyomas, respectively (p=0.002). Conclusion: Uterine leiomyomas did not adversely affect the prognosis of patients with endometrial carcinoma. Moreover, lymph node involvement was less common, and stages were lower in patients with leiomyomas.
Authors and Affiliations
Önder Sakin, Ramazan Denizli, Zehra Meltem Pirimoğlu, Ali Doğukan Anğın, Muzaffer Seyhan Çıkman, Gökhan Gülyaşar
Keywords
Related Articles
- EP ID EP685117
- DOI 10.4274/tjod.galenos.2020.70104
- Views 181
- Downloads 0
Systematic review and meta-analysis of ropivacaine use in laparoscopic hysterectomy
To assess the efficacy of all forms of ropivacaine administration for the management of pain and opioid use, specifically in patients undergoing laparoscopic hysterectomy. We searched PubMed, Cochrane CENTRAL, Web of Sci...
Blake’s pouch cyst: Prenatal diagnosis and management
Objective: This study aimed to present the characteristic features of 19 patients who were diagnosed as having Blake’s pouch cyst (BPC) at our center. Materials and Methods: Nineteen patients diagnosed as BPC between 20...
Antenatal pentoxifylline therapy to prevent endotoxin-induced fetal injury in the preterm goat model
Objective: Pentoxifylline (PTX) has immunomodulatory properties and is known to reduce sepsis-associated infant mortality. We aimed to evaluate maternal oral and intra-amniotic administration of PTX for the prevention of...
The relationship between isolated pes equinovarus and aneuploidies and perinatal outcomes: Results of a tertiary center
Objective: Congenital pes equinovarus (PEV) is the most common congenital deformity of the foot, characterized by plantar flexion with a frequency of 0.2-0.3%. It can be diagnosed from the 12th week of pregnancy. Non-iso...
A randomized pilot study of electro-acupuncture treatment for hysterosalpingography pain relief and related anxiety
Objective: To investigate the effect of acupuncture on reducing pain and anxiety related to hysterosalpingography (HSG). Materials and Methods: A total of 107 patients planned to undergo HSG were randomly separated into...