The effects of oral vitamin A (retinol) on chemically–induced corneal ulcer in guinea pigs
Journal Title: Asian Pacific Journal of Health Sciences - Year 2016, Vol 3, Issue 2
Abstract
The effects of the healing propensity of vitamin A (retinol), a vital micro-nutrient were studied on chemically–induced corneal ulcers in guinea pigs. Corneal regeneration following alkaline injury was studied by fluorescent dye staining of the cornea under cobalt blue light, while digital photographs were taken every 6 hours. Results showed that administration of vitamin A syrup reversed the epithelial damage, produced accelerated wound healing, restored the eyelid status, light-reflex and corneal lustre, abolished corneal infiltrates and lacrimation in the treated group while the positive control (untreated) group had slow healing process as the ulceration continued unhindered. It is, therefore, concluded that vitamin A administered systemically facilitates the rate of epithelial regeneration in the cornea following traumatic injury or damage.
Authors and Affiliations
Dr. Igwe S. A.
Keywords
Related Articles
- EP ID EP524236
- DOI 10.21276/apjhs.2016.3.2.30
- Views 156
- Downloads 0
Aqueous extract of Geniosporum prostratum (L)Benth plant and its role in reducing oxidative stress in STZ- induced diabetic rats
To evaluate aqueous extract of Geniosporum prostratum (L) Beanth in normal and streptozotocin (STZ) induced diabetic rats. Diabetes was induced by intraperitoneally (i.p) streptozotocin (60mg/kg)adult male albino wister...
Correlation of body mass index, degree of airflow obstruction, dyspnea scale, and exercise index with pulmonary hypertension
Introduction: Cardiovascular disease is major comorbidity and most frequent disease coexisting with chronic obstructive and pulmonary disease (COPD). BODE (body mass index, degree of airflow obstruction, dyspnea scale an...
Evolutionary role of the community pharmacist: A review
Pharmacy is a science related to the preparing and dispensing of drugs. In the past pharmacist, only dispense the medicines. With the passage of time, pharmacists gained his position in multidisciplinary provision of hea...
A Comparative Study of Racedrotril and Single Dose Octreotide in Acute Diarrhoea
To assess the efficacy of single dose of octreotide and compare it with another antisecretory agent racecadotril in the management of acute infective diarrhoea. A Randomised control study was carried out on the acute dia...
A Study of Association of Mean Platelet Volume and Ischaemic Stroke
Background: Cerebrovascular diseases include some of the most common and devastating disorders. Mean platelet volume (MPV) is a physiological variable of haemostatic importance. Large platelets are more reactive, produce...