The Efficacy of Flavonoid Antioxidant from Chocolate Bean Extract: Prevention of Myocyte Damage Caused by Reperfusion Injury in Predominantly Anaerobic Sports
Journal Title: Malaysian Orthopaedic Journal - Year 2012, Vol 6, Issue 2
Abstract
Background: Use of predominantly anaerobic energy systems such as that seen in 800-meter athlete runners disrupts mitochondrial function as an energy source. Furthermore, it produces free radical substances and causes myocyte damage. Malondialdehyde (MDA) plasma concentrations correlate with free radical levels and are therefore predictive of cell damage. Objective: To analyse the effect of flavonoid antioxidant from chocolate bean extract for prevention of lipid peroxidation of myocyte membranes caused by free radical substances in athletes partaking in predominantly anaerobic sports. Materials and Methods: The study of population consisted of 16 junior athletes who compete in 800-meter races. This was a randomized experimental study. Subjects were divided into two groups, chocolate bean extracts and placebo groups, and then practiced regularly for 14 days. All subjects were assessed on day 15. Results were analysed statistically using paired t test, ANOVA and Duncan tests. Results: Concentrations of MDA were reduced in flavonoid group. Conclusion: Flavonoid antioxidant from chocolate bean extract may prevent myocyte damage was caused by reperfusion injury.
Authors and Affiliations
HN Rasyid, YD Ismiarto, R Prasetia
Keywords
Related Articles
- EP ID EP303464
- DOI 10.5704/MOJ.1207.012
- Views 71
- Downloads 0
Complex Proximal Humeral Fracture Fixation with PHILOS Plate using Minimal Invasive Percutaneous Plate Osteosynthesis (MIPPO) Technique: A Series of 30 Patients
Introduction: Proximal humerus fracture fixation using plate osteosynthesis depends on the quality of the bone, design of the fixation devices and intra-operative soft tissue dissection. This study evaluates the function...
Primary Unreamed and Unlocked Intramedullary Nailing of Femoral Shaft Fractures
In this retrospective study, we present our experience using open Küntscher nailing (K-nailing) which is still performed in developing countries for femoral fractures. Of 157 acute fractures treated between January 2003...
Outcome of Primary Cemented Bipolar Hemiarthroplasty compared with Dynamic Hip Screw in Elderly Patients with Unstable Intertrochanteric Fracture
Introduction: Although the treatment of choice for unstable intertrochanteric fractures in elderly patients has been internal fixation for a long time, several studies have shown mechanical and technical failures. Primar...
An Unusual Case of “Locking” of the Knee Four Years Post Fixation of an Open Supracondylar Femur Fracture
The introduction of locking plate devices have increased the number of viable options for fracture fixation. An understanding of the indications and contraindications and technique limitations are important to minimise a...
Two-Stage Surgery for a Large Cervical Dumbbell Tumour in Neurofibromatosis 1: A Case Report
Spinal neurofibromas occur sporadically and typically occur in association with neurofibromatosis 1. Patients afflicted with neurofibromatosis 1 usually present with involvement of several nerve roots. This report descri...