The Efficacy of Intraoperative Ketamine-Haloperidol for Prevention of Catheter-related Bladder Discomfort After Lumbar Spinal Stenosis Surgery

Journal Title: Oman Medical Journal - Year 2019, Vol 34, Issue 3

Abstract

Objectives: Catheterization of urinary bladder during surgery frequently leads to agitation of the patient in the recovery room, especially in those patients who remain catheterized after gaining consciousness. We hypothesized that administration of a combination of ketamine-haloperidol (KH) before urinary catheterization would reduce the incidence of catheter-related bladder discomfort (CRBD) while reducing some adverse effects of ketamine in the postoperative period. Methods: A total of 119 male patients who underwent lumbar spinal stenosis surgery were randomized into three groups. The KH group consisted of 39 patients who received KH just before urinary catheterization. The second arm of the study including 40 patients who received pethidine-haloperidol (PH). The control (C) group consisted of 40 patients who received normal saline as a placebo. We sought to determine the incidence and severity of CRBD at arrival in recovery and one, six, and 24 hours after. Results: The incidence of CRBD upon arrival in the recovery room was 17.9% in the KH group, and 52.5% and 55% in the PH and C groups, respectively. The incidence of CRBD was significantly lower in the KH group at arrival in the recovery room. The severity of CRBD was lower in the KH group at one and six hours of surgery (p < 0.007). There was no significant difference 24 hours after surgery. Conclusions: Intravenous administration of KH before urinary catheterization effectively decreases the incidence and severity of postoperative CRBD while reducing adverse effects attributed to ketamine.

Authors and Affiliations

Mohammad Reza Khajavi, Nazafarin Kamalzadeh, Pejman Pourfakhr, Reza Shariat Moharari, Farhad Etezadi

Keywords

Related Articles

Breast Cancer Knowledge and Breast Self-Examination Practices Among Female University Students in Kampala, Uganda: A Descriptive Study

Objective: The purpose of the study was to assess female university students’ knowledge of breast cancer risk factors, signs and symptoms, and identify breast self-examination (BSE) practices. Using this information we a...

Attention Deficit Hyperactivity Disorder and Parental Factors in School Children Aged Nine to Ten Years in Muscat, Oman

Objectives: The objectives of this study were to determine the prevalence of attention deficit hyperactivity disorder (ADHD) and specific parental risk factors that may contribute to the development of ADHD in children....

Cancer Incidence in Oman (1996–2015)

Cancer remains a major public health problem worldwide. In 2018, the International Agency for Research on Cancer (IARC) estimated that over 18 million new cases of cancer were diagnosed and nearly 10 million people lost...

Immunophenotypic Characteristics of T-Acute Lymphoblastic Leukemia in Omani Patients: A Correlation with Demographic Factors

Objectives: To study and classify the immunophenotypic characteristics of Omani patients diagnosed with T-cell acute lymphoblastic leukemia (T-ALL) and to correlate the results with age and gender as well as biological f...

Acceptability of Reminders for Immunization Appointments via Mobile Devices by Mothers in Ilorin, Nigeria: A Cross-sectional Study

Objectives: Immunization coverage in Nigeria remains low despite the protection it confers. Reminders via mobile phones may be deployed as a means of improving vaccination coverage but requires the participation and coop...

Download PDF file
  • EP ID EP560628
  • DOI 10.5001/omj.2019.41
  • Views 48
  • Downloads 0

How To Cite

Mohammad Reza Khajavi, Nazafarin Kamalzadeh, Pejman Pourfakhr, Reza Shariat Moharari, Farhad Etezadi (2019). The Efficacy of Intraoperative Ketamine-Haloperidol for Prevention of Catheter-related Bladder Discomfort After Lumbar Spinal Stenosis Surgery. Oman Medical Journal, 34(3), 212-217. https://europub.co.uk/articles/-A-560628