The efficacy of rituximab in adult frequently relapsing minimal change disease
Journal Title: Clinical Kidney Journal - Year 2017, Vol 10, Issue 1
Abstract
Corticosteroids are the basis of treatment for nephrotic syndrome due to minimal change disease (MCD), but 25% of patients have frequently relapsing nephrotic syndrome (FRNS) and 30% become steroid dependent. Prolonged use of conventional immunosuppressants causes significant toxicity. Rituximab (RTX) is now included in guidelines for childhood MCD. Evidence for use in adult MCD is limited. We describe a single-centre experience of RTX use in adult MCD.
Authors and Affiliations
Catherine King, Sarah Logan, Stuart W. Smith, Peter Hewins
Keywords
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- EP ID EP679673
- DOI 10.1093/ckj/sfw100
- Views 29
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