THE EFFICACY OF SACCHAROMYCES CEREVISIAE AND CANDIDA KRUSEI IN REDUCTION OF AFLATOXIN B1 THAT PRODUCED BY ASPERGILLUS FLAVUS IN VITRO
Journal Title: World Journal of Pharmaceutical Research - Year 2018, Vol 7, Issue 1
Abstract
Aflatoxin B1 (AFB1) is a potent hepatotoxic and hepatocarcinogenic mycotoxin produced by some filamentous fungi like Aspergillus flavus and Aspergillus parasiticus. This toxin widely contaminates food and feedstuffs causing health problems to the human and animals when consuming the contaminated food. This study compared between two of well-known biocontrol yeasts Saccharomyces cerevisiae (S.c.) and Candida Krusei (C.k.) in vitro to evaluate their efficiency in control A.flavus growth and AFB1 reduction. The results revealed a significant ability of both yeasts to inhibit fungal growth area (3.9, 8.14 mm2) respectively comparing with the control (71.34 mm2). Both yeast species (Sc. and C.k.) were significantly reduced 250 ng of AFB1 to the non-detectable levels after 48h of incubation in broth culture.
Authors and Affiliations
Al-Saad L. A.
BIOCHEMICAL STUDIES ON UROKINASE PLASMINOGEN ACTIVATOR (UPA) AS FIBROTIC MARKER IN HEPATITIS C PATIENTS
Introduction: Biopsy is standard procedure in the evaluation of liver diseases, but it is an invasive method subject to sampling error. Aim: Non-invasive methods for the assessment of liver fibrosis are clinically import...
AN AYURVEDIC CONCEPT OF SUTIKA PARICHARYA AND CLINICAL IMPORTANCE OF SAMANYA PARICHARYA – A REVIEW
The transformation of female, from a woman to mother is the happiest lifetime event, but this happiness is gained only after undergoing tremendous physical exertion during labour, so old people used to term 'labour' as w...
IN VITRO ASSAYS TO INVESTIGATE THE ANTI-INFLAMMATORY ACTIVITY OF HERBAL EXTRACTS: A REVIEW
The article reviews recent studies on the anti-inflammatory effects of herbal extracts with emphasis on different assays that are frequently used to test the in-vitro anti-inflammatory activity of herbal constituents. Pr...
EVALUATION OF POSTGRADUATE HOSPITAL EDUCATION ENVIROMENT MEASURE AMONG TRAINEE IN MILITARY HOSPITALS IN TAIF, SAUDI ARABIA
Background: The learning environment during residency program can affect the quality of trained doctors and their future career. In this study we aim to assess the learning environment of residents in military hospitals...
VINCRISTINE INDUCED VOCAL CORD PARALYSIS IN PATIENT WITH DIFFUSE LARGE B-CELL LYMPHOMA: A CASE REPORT
We described a 60 years old male patient with diffuse large B-cell lymphoma who developed vincristine-induced vocal cord paralysis. Vincristine-induced vocal cord paralysis is rare but potentially lifethreatening complic...