The Ethanolic Extract of Beetroot (Beta Vulgaris) Ameliorates Some Red Cell Parameters In Phenylhydrazine-Induced Anaemic Rats
Journal Title: IOSR Journal of Nursing and health Science - Year 2018, Vol 7, Issue 4
Abstract
Beetroot is a plant with high nutritional and medicinal value. This study investigated the antianaemic effect of beetroot on wistar rats. 25 male wistar rats were randomly assigned into 5 groups (n=5) thus: control, anaemic, beet(only), beet(LD) and beet(HD) groups. Except for control (0.2ml normal saline) and beet(only) groups, other groups were induced with anaemia using phenylhydrazine (60mg/kg) intraperitoneally on days 1- 3. Beet(only), beet(LD) and beet(HD) groups received oral standard (200mg/kg), low (100mg/kg) and high (400mg/kg) doses of beetroot extract respectively daily for 14 days. Results show that RBC count, Hb concentration and PCV decreased by (38%, 31% and 20% respectively) in anaemic group compared with control. RBC, Hb concentration and PCV increased in beet(LD) (68%, 57% and 30% respectively) and beet(HD) (87%, 69%,and 35%respectively) groups compared with anaemic group. MCV increased (36%) in anaemic group compared with the control but decreased in beet(LD) (23%) and beet(HD) (24%) groups compared with anaemic. MCHC, decreased in the anaemic (8%) but increased slightly in the BeetLD (7%) and BeetHD (8%) groups compared with the anaemic group. All the red cell indices increased slightly in the beetONLY group compared with control. Beetroot extract demonstrated anti-anaemic effect and is effective in defending the body against anaemia associated diseases.
Authors and Affiliations
Favour. Nyoh Beshel, Justin Atiang Beshel, Ekamma Edet Ante
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