The Evaluation of Amygdala Volumes in Adolescents with Bipolar Disorder Type I
Journal Title: Turkish Journal of Child and Adolescent Mental Health - Year 2019, Vol 26, Issue 2
Abstract
Objectives: The aim of the present study is to investigate whether the variables of the disorder affect amygdala volumes in the adolescents with Bipolar Disorder (BD) type I and to compare the possible amygdala volume changes with healthy adolescents. Materials and Methods: Seventeen adolescents aged between 13 and 19 years, who had BD type I according to Diagnostic and Statistical Manual of Mental Disorders-IV criteria that was either already been followed up or got the diagnosis after their admission to Dokuz Eylül University Faculty of Medicine, Department of Child and Adolescent Psychiatry between May 2008 and October 2008, were included in the study. Twelve adolescents between 13 and 19 years old and without any psychiatric diagnosis were included in the healthy control group. The magnetic resonance imaging (MRI) scans of all participants were performed by using an MRI machine with 1.5 Tesla power (Gyroscan Intero, Philips, Netherlands) and standard head coils. The MRI scans of the cases were made during euthymic phase. The phase of euthymia was defined according to Young Mania Rating Scale and Hamilton Depression Rating Scale. Results: The evaluation and comparison of both right and left amygdala volumes between the patient and the control group revealed no significant difference. However, in the patient group, negative correlation was found between right and left amygdala volumes and the duration of the disorder (for the right amygdala p=0.026; for the left amygdala p=0.031). Conclusion: The differences detected in amygdala volumes by structural MRI scans in adolescent and adult BD samples may reflect underlying pathophysiologic differences between the early onset and the late onset of the disorder.
Authors and Affiliations
Birsen Şentürk Pilan, F. Neslihan Emiroğlu, Handan Güleryüz, Taner Çelik, Ahmet Ergin Çapar, Hülya Ellidokuz, Ümit Şahin, Süha Miral
Keywords
Related Articles
- EP ID EP48050
- DOI 10.4274/tjcamh.galenos.2019.2019.03.05
- Views 425
- Downloads 0
Multimodal Treatment Approach in a Child with Selective Mutism
Selective mutism is a disorder that begins in childhood and is characterized by lack of speech in certain social settings in which the child is expected to speak, although he/she has the ability to speak and speaks norma...
Child Mental Health Services in Emergency Department of a University Hospital
Objectives: It is aimed to present pediatric psychiatry consultations requested from children and adolescents applying to the emergency departments of a university hospital and to evaluate the mental health services prov...
Symptoms Extending from Identity Confusion to Personality Pattern, Autistic Spectrum to Psychotic Spectrum Via an Adolescent Case
Diagnostic and Statistical Manual of Mental Disorders and International Classification of Diseases and Associated Health Problems classify mental disorders as discrete categories. However, we often see in our clinical pr...
Intestinal Malrotation Confused with Psychiatric Disorder in a Child: A Case Report
We aim to explore the importance of early differential diagnosis of an organic etiology such as intestinal malrotation and psychiatric disorder. We present a child with an intestinal malrotation, who had no symptoms unti...
Preventing the Psychological and Developmental Outcomes of Child Maltreatment
This study aims to illustrate the long-term effects of maltreatment during childhood and to provide a comprehensive picture of the predictors of this significant problem. The reflections of child maltreatment in Turkey a...