The evaluation of efficacy of subtenon triamcinolone injection combined with focal laser photocoagulation in diabetic macular edema
Journal Title: Dicle Tıp Dergisi - Year 2012, Vol 39, Issue 2
Abstract
Objectives: The aim of this study was to investigate efficacy and safety of subtenon triamcinolone (ST) in combination with focal laser photocoagulation in diabetic macular edema (DME). Materials and methods: Medical records of patients with DME, treated with 40 mg subtenon injection of triamcinolone acetonid prior to focal laser photocoagulation were retrospectively analyzed. Seventeen eyes of 17 patients with DME were enrolled in the study. All patients underwent a comprehensive ophthalmological examination before the treatment. Efficacy of the treatment after ST injection was evaluated by visual acuity and flourescein angiography (FA). Follow-up visits were performed at 1st, 3rd, 6th and 12th months. Repeated measures ANOVA was used for statistical analysis. Results: The mean age was 61.5 ± 8.7 years and the mean visual acuity in the study eyes was 0.22 ± 0.13 before the treatment, 0.39 ± 0.15 at 1st month, 0.36 ± 0.18 at 3rd month, 0.33 ± 0.15 at 6th month and 0.34 ± 0.16 at 12th month. The differences in the visual acuity before the treatment and follow-up visits were significant (p ˂0.05). Visual acuity was increased in 13 (%76,4) patients, decreased in 1 (%5,8) and unchanged in 3 (%17,6). Conclusion: Injection of 40 mg of triamsinolon via subtenon route combined with focal laser photocoagulation is a safe and beneficial treatment in cases of DME
Authors and Affiliations
Özgür İlhan, Mesut Coşkun, Nilüfer İlhan, Emre Ayıntap, Uğurcan Keskin, Esra Tuzcu, Hüseyin Öksüz
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