The evaluation of relationship between neutrophil-to-lymphocyte ratio and slow coronary flow
Journal Title: Dicle Tıp Dergisi - Year 2013, Vol 40, Issue 4
Abstract
Objective: The aim of this study was to investigate the correlations between leukocyte counts, the neutrophil-tolymphocyte ratio (NLR), and slow coronary flow (SCF). Methods: We evaluated 135 patients undergoing coronary angiography (CAG) within coronary artery disease (CAD) indication. We divided patients into three groups according to the CAG findings. Group 1 consisted of 45 patients with an SCF pattern; group 2 consisted of 45 patients with at least 50% lumen narrowing in at least one epicardial coronary artery; and group 3 (control group) consisted of 45 patients with normal coronary arteries. The quantification of the coronary flow was assessed using the thrombolysis in myocardial infarction (TIMI) frame count method for each of the coronary arteries. Blood samples were collected from the patients after a 12 h overnight fasting. The NLR ratio was calculated from the automated complete blood count. Results: NLR in CAD was higher than in both the SCF and control groups (p=0.008, p<0.001, respectively). However, there was no statistically significant difference between SCF and control group (p=0.768). Neutrophil counts in CAD were higher than in both SCF and control groups, but only the difference between CAD and SCF groups was statistically significant (p=0.010). Conclusion: Our study revealed that circulating neutrophil counts and NLR were related to the coronary artery disease, as expected. Key words: Neutrophil-to-lymphocyte ratio, leukocyte subtype, slow coronary flow, coronary artery disease
Authors and Affiliations
Mehmet Ertürk, Özgür Surgit, Ahmet Yalcın, Fatih Uzun, Muhammet Gürdoğan, İbrahim Aktürk, Ender Öner, Ali Birant, Abdurrahman Eksik
Keywords
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- EP ID EP125963
- DOI 10.5798/diclemedj.0921.2013.04.0329
- Views 139
- Downloads 0
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