The Evaluation of the Relationship Between the Frequency of Urologic Symptoms and the Disease Progression with Multiple Sclerosis
Journal Title: The New Journal of Urology / Yeni Üroloji Dergisi - Year 2020, Vol 15, Issue 1
Abstract
Objektive: Our aim is to determine the relationship between Multiple Sclerosis (MS) disease progression and urological symptoms. Meterial and Methods: We enrolled patients with Newly Diagnosed MS (n: 11), RRMS (n: 9), SPMS (n:6) and healthy control subjects (n:10). Neurological examination was done in all groups. Furthermore, patient groups were evaluated with EDSS (Expanded Disability Status Scale) and MSFC (functional capacity in multiple sclerosis scale). Routine blood biochemistry tests were done. All patients and the subjects in the control group were evaluated in regard to lower urinary tract symptoms by the following questionnaires: incontinence and sexual function in terms of IPSS (International Prostate Symptom Score), ICIQ -SF (International Incontinence Questionnaire), IIEF (International Index of Erectile Dysfunction Test) and FSFI (Female Sexual Function Index). In addition, all the patients were evaluated by urodynamic studies in order to examine the voiding function. Results: There were no differences between the group in respect to age, years of education and gender. As the disease duration increase, the frequency of incontinence was found to increase. PSS, IPSS-QOL, ICIQ-SF scores of newly diagnosed MS, RRMS, SPMS and healthy control groups were statistically significant. There was a correlation between EDSS score and urological symptoms. There was no relationship between disease duration and urological symptoms. Due to inadequate number of male patients in the study, IIEFscore did not differ significantly between the groups. There was no relationship between EDSS score, disease duration and IIEF. Due to inadequate number of the female patients in the study, FSFI score did not differ significantly between the groups. There was no relationship between EDSS score, disease duration and FSFI. The most attractive result of our study is the urodynamic detrusor overactivity (DO). Bladder capacity was found to be low in SPMS. EDSS score and 25 step walk score increases while bladder capacity has been reduced. There was no relationship shown between duration of disease and bladder capacity. Conclusion: Patients with Multiple Sclerosis (MS) have a very high prevalence of lower urinary tract symptoms. These symptoms have a great impact on patient quality of life. Therefore, early recognition and treatment is an important step in care of MS patients.
Authors and Affiliations
Ozden,H. , Yildirim,A. , Sunter,G. , Gunal,D. , Agan,K.
Keywords
Related Articles
- EP ID EP679996
- DOI https://doi.org/10.33719/yud.601359
- Views 232
- Downloads 0
Urinary Tract Infection and Predisposing Factors in Patients with Ureteral Stents
Objective: We aimed to demonstrate the relationship between urine analysis/culture and significant urinary tract infection in patients with Double-J stent (DJS) and thus prevent unnecessary antibiotic use and overtre...
Endoscopic Surgery of Urethral Strictures: Laser Versus Knife
Objective: We aimed to compare the efficiency of cold knife urethrotomy and laser urethrotomy in endoscopic surgery of urethral strictures. Material and Methods: A total of 171 patients were evaluated retrospectivel...
The Effectiveness of Real Time Elastography: May the Corticomedullary Strain Rate Be Used in the Diagnosis and Follow-Up of Urinary Obstruction?
Objective: To investigate the utility of corticomedullary strain ratio (SR) in the diagnosis and follow-up of urinary obstruction. Material and Methods: Forty volunteer patients (26 males, 14 females) aged between 1...
The Role of Neutrophil-lymphocyte Rate in Treatment Resistant Patients in Treatments With Urinary Tract Infection
Objective: To evaluate the role of neutrophil- lymphocyte ratio in treatment resistance and follow-up in pregnant women with lower urinary tract infection. Materials and Methods: The data of 88 pregnant women with U...
Comparison Of Different Anesthesia Methods In Patients With Percutaneous Nephrolithotomy
Objective: Nowadays, percutaneous nephrolithotripsy (PCNL) is the first choice of minimally invasive treatment for large and complex kidney stones. In this retrospective study, we compared the efficacy and safety of...