The feasibility of using ursodeoxycholic acid in the treatment of patients with non-alcoholic fatty liver disease: a clinical case
Journal Title: Гастроентерологія - Year 2018, Vol 52, Issue 3
Abstract
Non-alcoholic fatty liver disease (NAFLD) is on a leading position among chronic liver diseases. In addition, the pathogenesis of NAFLD has not been fully studied for today. Some authors suggest that NAFLD is one of the components of metabolic syndrome (MS), considering it as a liver manifestation of MS. The article presents current views on the treatment of patients with NAFLD. The theoretical aspects of using ursodeoxycholic acid (UDCA) and the possibility of its application in patients with a combination of NAFLD and MS are also presented. As an example, the feasibility and efficacy of UDCA administration to the patient L. with NAFLD and MS (glucose intolerance, arterial hypertension, obesity) has been demonstrated. The prescription of Ursofalk to the patient L. is pathogenetically grounded due to the hypocholesterolemic, cytoprotective, antioxidant, anticholestatic and other its beneficial effects. UDCA can be considered as an effective and safe drug for the treatment of patients not only with NAFLD, but also with MS, diseases of the cardiovascular system and obesity.
Authors and Affiliations
Ye. S. Sirchak
Keywords
Related Articles
- EP ID EP388619
- DOI 10.22141/2308-2097.52.3.2018.141848
- Views 62
- Downloads 0
Features of Pancreatic Pathology in Children
Background. The prevalence of pancreatitis in children with digestive disorders is 5–25 %. Aim of research: to determine the prevalence of pancreatic pathology in children. Material and methods. The research was conducte...
The Experience of Using Parenteral Nutrition in the Treatment of Liver Insufficiency
The article provides the data about positive experience of aminoplasmal hepa 10% application as a preparation of parenteral nutrition, which evens out the ratio of branched-chain amino acids and aromatic amino acids, nor...
Main Indicators of Surgical Care for Patients with Biliary Pathology at the Secondary Level
The authors analyzed the prevalence of cholelithiasis, chronic cholecystitis (CC) and cholangitis, the incidence of this pathology, as well as surgical activity and postoperative mortality due to surgical interventions o...
Comprehensive therapy of gastroesophageal reflux disease combined with anxiety-depressive states in antiterrorist operation participants
Background. The purpose was to establish the incidence and severity of anxiety-depressive disorders in antiterrorist operation (ATO) participants with different clinical endoscopic forms of gastroesophageal reflux diseas...
Modern Approaches to Optimization of the Diagnosis and Treatment of Exocrine Pancreatic Insufficiency
The article describes the etiology and current diagnostic methods of investigation of exocrine pancreatic insufficiency, in particular non-invasive 13C-mixed triglyceride test, allowing not only to determine indirectly t...