The features of esophageal daily pH-monitoring depending on the clinical form of gastroesophageal reflux disease in type 2 diabetic patients
Journal Title: Міжнародний ендокринологічний журнал - Year 2018, Vol 14, Issue 5
Abstract
Background. The purpose of the study was to determine the features of esophageal daily pH-monitoring depending on the clinical form of gastroesophageal reflux disease in type 2 diabetic patients. Material and methods. Eighty-two patients with type 2 diabetes mellitus and gastroesophageal reflux disease were examined. All patients underwent daily pH-monitoring. Results. The time percentage when esophageal pH was < 4 almost equally exceeded such parameter in the control group (31.7 ± 2.3 % in patients with the esophageal form of gastroesophageal reflux disease and 32.7 ± 2.9 % in patients with extra-esophageal form against 4.5 ± 0.3 % in the control group; p < 0.01). Conclusions. In type 2 diabetic patients with esophageal form of gastroesophageal reflux disease daily pH-monitoring revealed pH < 4 in the esophagus mostly in vertical position, and in patients with extra-esophageal form — in horizontal position. The esophageal pH disturbance in type 2 diabetic patients with esophageal form of gastroesophageal reflux disease is associated with candida esophagitis, whereas in patients with extra-esophageal manifestations — with duodeno-gastro-esophageal reflux (r = 0.84; p < 0.01; r = 0.71; p < 0.05, respectively).
Authors and Affiliations
Yo. I. Pichkar, Ye. S. Sirchak, M. P. Stan, Piotr Oleksyk
Using the principle of multiparametric ultrasound for the diagnosis of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus
Background. The purpose of this study is evaluation of using the principle of multiparametric ultrasound (mp-US) for the diagnosis of nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (T2...
Pituitary Cushing’s syndrome: analysis of the newly diagnosed cases
A description of 4 cases of newly diagnosed Cushing’s pituitary syndrome (PCS) is presented. The feature of the first case of PCS is the manifestation of the disease in the form of 2 spontaneous fractures of the foot bo...
Primary Hyperparathyroidism: Etiology, Pathogenesis, Clinical Picture, Diagnosis, Treatment, Quality of Life (Review of Literature)
The author provide a literature review of the data for the last 10–15 years on the problem of primary hyperparathyroidism (PHPT). PHPT was first described in 1943, but interest to the diseases of the parathyroid glands g...
Endocrine Ophthalmopathy in Autoimmune Thyroid Diseases
The article presents modern data about risk factors, mechanisms of development, clinical features of endocrine ophthalmopathy, as well as information regarding current approaches to diagnosis, treatment and prevention of...
The use of Nucleo C.M.P. Forte in the comprehensive treatment of diabetic polyneuropathy
Background. Diabetes mellitus (DM) is one of the socially significant diseases. At the time of manifestation of DM, up to 6 % of patients have signs of diabetic polyneuropathy (DPN), after 5 years of the disease, they a...