The features of esophageal daily pH-monitoring depending on the clinical form of gastroesophageal reflux disease in type 2 diabetic patients
Journal Title: Міжнародний ендокринологічний журнал - Year 2018, Vol 14, Issue 5
Abstract
Background. The purpose of the study was to determine the features of esophageal daily pH-monitoring depending on the clinical form of gastroesophageal reflux disease in type 2 diabetic patients. Material and methods. Eighty-two patients with type 2 diabetes mellitus and gastroesophageal reflux disease were examined. All patients underwent daily pH-monitoring. Results. The time percentage when esophageal pH was < 4 almost equally exceeded such parameter in the control group (31.7 ± 2.3 % in patients with the esophageal form of gastroesophageal reflux disease and 32.7 ± 2.9 % in patients with extra-esophageal form against 4.5 ± 0.3 % in the control group; p < 0.01). Conclusions. In type 2 diabetic patients with esophageal form of gastroesophageal reflux disease daily pH-monitoring revealed pH < 4 in the esophagus mostly in vertical position, and in patients with extra-esophageal form — in horizontal position. The esophageal pH disturbance in type 2 diabetic patients with esophageal form of gastroesophageal reflux disease is associated with candida esophagitis, whereas in patients with extra-esophageal manifestations — with duodeno-gastro-esophageal reflux (r = 0.84; p < 0.01; r = 0.71; p < 0.05, respectively).
Authors and Affiliations
Yo. I. Pichkar, Ye. S. Sirchak, M. P. Stan, Piotr Oleksyk
Draft Concept of the State Target Social Program «Diabetes Mellitus for the Period until 2018»
.
The particularities of management of patients with malignant tumors of adrenal medulla
Pheochromoblastoma is a tumor developing from adrenal medulla and characterizing the severe course and high mortality level (15 %). Its severity is due to presence of not only malignancy but also catecholamine hyperprodu...
Pathomorphosis of the metabolic phenotype osteoarthritis: the role of obesity, diabetes and hypothyroidism (age and gender features)
Background. Osteoarthritis (OA) is one of the most common diseases of the musculoskeletal system, which is characterized by a high level of comorbidity. The growing prevalence of obesity, diabetes mellitus (DM) and hypot...
Relationship between Adipokines and Body Mass Index in Patients with Type 2 Diabetes Mellitus
An examination of 102 patients with type 2 diabetes mellitus was aimed to study the features of correlations of insulin resistance markers, body mass index and adipokines. Correlation analysis revealed reliable connectio...
Vitamin D status in the population of the Western region of Ukraine
In this lecture, we discuss the main causes of the vitamin D insufficiency and deficiency in the Western region of Ukraine, as well as present data on the incidence of vitamin D deficiency among various population groups...