The first reported case of a variant of Mal de Maleda of the Gamborg-Nielsen type in an Egyptian origin patient
Journal Title: Nasza Dermatologia Online - Year 2018, Vol 9, Issue 2
Abstract
Mal de Meleda is a rare genodermatosis with an autosomal recessive inheritance. Mutations in the SLURP1 gene are the cause of this disease. Clinically, it is characterized by progressive palmoplantar hyperkeratosis exhibiting a transgradiens pattern extending to the dorsal aspects of the hands and feet in a glove and stocking pattern. It is also associated with hyperhidrosis, nail changes, subungual hyperkeratosis and perioral erythema. Here we report the first case of Gamborg-Nielsen variant of Mal de Meleda disorder in a patient of an Egyptian origin.
Authors and Affiliations
Khalid M. Al-Husain
Keywords
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- EP ID EP279303
- DOI 10.7241/ourd.20182.9
- Views 60
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