The Gene Therapy – Exploring the Challenges…
Journal Title: Saudi Journal of Medicine - Year 2018, Vol 3, Issue 5
Abstract
Abstract:Genes are the smallest functional units of the genetic system, which control the development and function of all organisms. A gene is a linear sequence of DNA that codes for a particular protein. Gene therapy is based on principle that a normal gene is inserted to compensate for a nonfunctional gene and abnormal gene can be repaired through selective reverse mutation. It uses purified preparations of a gene or a fraction of gene to treat diseases. Gene therapy can be used to treat wide range of diseases ranging from single gene disorder to multi-gene disorder. It has variety of applications in the field of dentistry like in cancerous and precancerous condition, salivary gland disorders, autoimmune diseases, bone repair, DNA vaccination, bone repair etc. Keywords: Gene, Genetics, DNA, RNA, Gene transfer.
Authors and Affiliations
Gaurav Arya, Anandita Gupta Arya
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