The histopathological effects of salvia officinalis on the kidney and liver of rats
Journal Title: Scientific Journal of Medical Science - Year 2013, Vol 2, Issue 3
Abstract
The aim of this investigationwas to evaluate some of the effects of aqueous leaf extract of Salvia officinalis on the kidney and liver of male Sprague Dawley rats. Ten Sprague-Dawley rats (7-11 weeks old)were randomly assigned into two groups; A and B. Aqueous extract of S.officinalis leaves (300 mg/kg body weight) was administered orally to therats in group B while the rats in group A received equal volume of normalsaline for 14d. At termination of treatment, the histopathology of the kidneyand liver were assessed. The kidney and the liver in the extract treated ratdisplayed organized and preserved histological profile. Our findings suggestthat S. officinalis has no deleterious effects on the kidney and liverof the rats.
Authors and Affiliations
D. A. Adekomi*| Department of Anatomy and Cell Biology, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria., T. D. Adeniyi| Department of Anatomy, College of Medicine, Osun State University, Osogbo, Osun State, Nigeria., A. M. Afodun| Department of Anatomy, Faculty of Basic Medical Sciences, University of Ilorin, Ilorin, Nigeria., K. K. Quadri| Department of Physiology, University of Lagos, Lagos, Nigeria.
Keywords
Related Articles
- EP ID EP1225
- DOI -
- Views 723
- Downloads 36
Incidence of malignancy in non toxic multi-nodular goiter an institutional experience
Objective: To determine the frequency of malignancy in multinodular goiter patients undergoing thyroid surgery in our institution. Place and duration of study: This is a prospective study was done on patients in t...
Risk factors for surgical treatment in gastric and colorectal cancer patients with low socioeconomic status
Surgery is the only potentially curative treatment option for gastric and colorectal cancer patients. Stage at diagnosis is the most important prognostic factor and closely related with socioeconomic status. Authors aime...
Treatment of obesity: medical managements
Obesity is a very complex illness. It is one of the most prevalent diseases in the western world, its importance lies in the comorbidities that surround it, as well as the predisposition to cardiovascular events and othe...
Retrospective evaluation of humane brucellosis in the region of Prizren
Prizren and its region for years considered an endemic area for brucellosis. The first case occurred in 1980 in Dragash, but subsequently occurred in Prizren and Rahovec.Aim: Epidemiological features of human brucellosis...
Hypolipidemic and hepato-protective effects of Alchornea cordifolia leaf extract in streptozotocin-induced diabetic rats
The study investigated the hypolipidemic and hepato-protectiveeffects of n-butanol fraction of Alchorneacordifolia leaf extract in streptozotocin-induced diabetic rats. To achievethis set objective, 16 hours fasted rats...