The histopathological effects of salvia officinalis on the kidney and liver of rats
Journal Title: Scientific Journal of Medical Science - Year 2013, Vol 2, Issue 3
Abstract
The aim of this investigationwas to evaluate some of the effects of aqueous leaf extract of Salvia officinalis on the kidney and liver of male Sprague Dawley rats. Ten Sprague-Dawley rats (7-11 weeks old)were randomly assigned into two groups; A and B. Aqueous extract of S.officinalis leaves (300 mg/kg body weight) was administered orally to therats in group B while the rats in group A received equal volume of normalsaline for 14d. At termination of treatment, the histopathology of the kidneyand liver were assessed. The kidney and the liver in the extract treated ratdisplayed organized and preserved histological profile. Our findings suggestthat S. officinalis has no deleterious effects on the kidney and liverof the rats.
Authors and Affiliations
D. A. Adekomi*| Department of Anatomy and Cell Biology, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria., T. D. Adeniyi| Department of Anatomy, College of Medicine, Osun State University, Osogbo, Osun State, Nigeria., A. M. Afodun| Department of Anatomy, Faculty of Basic Medical Sciences, University of Ilorin, Ilorin, Nigeria., K. K. Quadri| Department of Physiology, University of Lagos, Lagos, Nigeria.
Keywords
Related Articles
- EP ID EP1225
- DOI -
- Views 825
- Downloads 36
Correlation between clinical and radiological grading of osteoarthritis
Primary knee Osteoarthritis is a common condition affecting human beings after fourth decade of life. The diagnosis is based on a) Clinical presentation alone or b) on clinical and radiological findings or c) on clinical...
Prevalence of asthma in the subjects attending multi specialty centre OPD, Ballimaran, Delhi
The burden of Asthma in developing countries such as India isof sufficient magnitude to warrant its recognition as a priority in governmenthealth strategies. Particular resources need to be provided to improve the careof...
The study of effect of aqueous Cucurbita pepo linn seed extract on serum prolactin level of lactating female albino rats
Prolactin participation has been established for a growing number of physiological actions of these, the best studied is the stimulation of mammary gland development and induction of milk synthesis at the end of pregnanc...
Diffuse intraabdominal infection due to septic abortion but mimicking acute appendicitis
We present a case of diffuse intraabdominal infection which was misdiagnosed as appendicitis. The patient concealed having had sexual intercourse and being pregnant. She was diagnosed as intraabdominal infection after ac...
Oesophageal varices in patients with liver cirrhosis
About one third of cirrhotic patients with oesophageal varices (OV) develops an episode of oesophageal hemorrhage, and subsequently has high morbidity and mortality. Early detection and prevention of OV in these patients...