The Histopathological Spectrum of Spinal Nerve Root Lesions
Journal Title: International Journal of Research and Review - Year 2018, Vol 5, Issue 5
Abstract
Introduction- The diversity and complexity of anatomic structures located in the spinal region poses a great challenge to both the neuro-clinicians and neuropathologists displaying a wide heterogeneous spectrum of pathological lesions. The objective was to study the spinal nerve root lesions with reference to age groups, gender, anatomical location, the histopathological features with the clinico- radio- pathological correlation. Methods – This study is a retrospective and prospective analysis of spinal nerve root lesions diagnosed in the Neuropathology section over span of 10 years at a tertiary care and referral hospital. A total of 241 cases of spinal lesions were received during the study period out of which 80 cases of spinal nerve root lesions were reported. The clinical, radiological and therapeutic data was obtained from patients’ original case paper records and the lesions were analyzed according to their age, sex, duration, clinical signs and symptoms and distribution. All cases were analyzed by examining Hematoxylin and Eosin stained slides by light microscopy with use of special stains if needed. Results – Male predominance was seen in spinal nerve root lesions and 3rd and 4th decade age group was most commonly affected. These lesions were common in cervical region followed by thoracic region. Neoplastic lesions of spinal nerve roots were more frequently encountered than nonneoplastic lesions. Schwannoma (75 %) was commonest among spinal nerve root lesions followed by Neurofibroma (22.50 %). Conclusion – In our study, Schwannoma (75 %) was commonest among spinal nerve root lesions followed by Neurofibroma (22.50 %). The combination of clinical, radiological, and histopathological features forms the basis of the multi-disciplinary diagnostic approach towards spinal nerve root lesions.
Authors and Affiliations
Dr. Shantilal Mohanlalji Sisodia
Keywords
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