Thymidine phosphorylase expression and stromal vascularity in ductal carcinoma in situ of the breast

Records from 355 patients with DCIS in the Merseyside region were examined. Thirty two patients were identified who were known to have subsequently developed recurrent disease, 20 as recurrent DCIS and 12 as recurrent in...

Water transport becomes uncoupled from K+ siphoning in brain contusion, bacterial meningitis, and brain tumours: immunohistochemical case review

Specimens of normal human brain, contused brain, brain with bacterial meningitis, and brain tumours were immunolabelled for aquaporin 4 (AQP4) and Kir4.1. In normal brain tissue, AQP4 and Kir4.1 were dete...

α-Methylacyl CoA racemase (P504S): overview and potential uses in diagnostic pathology as applied to prostate needle biopsies

The diagnosis of prostatic adenocarcinoma remains dependent on the recognition of basic haematoxylin and eosin criteria. The discovery of α-methylacyl CoA racemase/P504S (AMACR/P504S) overexpressi...

Pathophysiology of meningococcal meningitis and septicaemia

Immunohistochemical analysis of adenocarcinoma of the small intestine: a tissue microarray study

Areas of invasive adenocarcinoma were identified on corresponding haematoxylin and eosin stained slides. Core biopsies of 0.6 mm in diameter were taken from each donor block and arrayed into a recipient paraffin block &#...