The impact of naturally stored energy reserve of the body in different proportions on type 2 Diabetes mellitus in Puducherry.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
Background: The increase in type 2 diabetes is directly related to the environmental risk factors, especially overweight and obesity, which superimposed on genetic predisposition results in progressive beta cell failure and insulin resistance. The relative risk for type 2 Diabetes increases as the Body mass index increases. Objective: 1. To assess the effect of various grades of obesity on type 2 Diabetes mellitus. 2. To correlate the effect of dyslipidemia as a consequence of obesity on type 2 DM. Materials and Methods: About 200 subjects were included in the study. The subjects were divided into 2 groups: Group 1 – 100 obese individuals (Obese normal + Obese Diabetic) and Group 2 – 100 non obese individuals ( Non obese normal + Non obese Diabetic). The body mass index was correlated with blood sugar and lipid profile. Statistical analysis were done using students unpaired t test. Results: The lipid profile increased significantly with increase in BMI. The lipid profile was significantly higher (p< 0.0001) in obese diabetic people when compared to non obese diabetics. The relative risk of diabetes increases with increasing BMI in the obese normal individuals. Conclusion: Obesity is an exaggeration of normal energy reserve of the body. It is the major contributor to the metabolic dysfunction involving lipid and glucose as well as complicating the clinical symptoms in subjects suffering from type 2 diabetes.
Authors and Affiliations
Dr. M. Priyatharshini, Dr . P. Muraliswaran, Dr. P. Kanagavalli, Dr. G. Radhika
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