The impactonmetifen on antioxidant and immune defense system of piglets unter nitrate poisoning
Journal Title: Біологія тварин - Year 2014, Vol 16, Issue 2
Abstract
The aim of study was to investigate and analyze the dynamic parameters of the antioxidant system and the resistance of pigs, in nitrate-nitrite load. The experiment was conducted on pigs of large white breed three mounth old. The materials for the study were blood samples. In the blood by known methods the total number of T-lymphocytes in general, phagocytic activity, the intensity of phagocytosis were defined. In serum the glutathione peroxidase activity, catalase activity, superoxide dismutase, lysocym active of serum, the bactericidal activity of serum content of circulating immune complexes of high molecular weight were investigated. We have found the antioxidant effect of Metifen which was feed at a dose of 0.9 mg/kg m.w. The positive effects of this remedy under antioxidant and immune system in nitrate loading have been established. In our studies it was shown by the growth performance of the level enzymatic antioxidant system namely, superoxide dismutase, glutathione peroxidase and catalase and increased resistance of the body piglets. Conduct of the study made it possible to further explore the impact of nitrates and nitrites in the body of pigs and make appropriate amendments to the concept of mechanisms of chronic nitrate-nitrite toxicity animals with regard to the status of the antioxidant system and the immune system.
Authors and Affiliations
C. Y. Leskiv, D. F. Gufriy
Keywords
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