The Impacts of Gianotti-Crosti Syndrome (Papular Acrodermatitis of Childhood) on the Quality of Life of Children
Journal Title: International Journal of TROPICAL DISEASE & Health - Year 2016, Vol 15, Issue 3
Abstract
Background: Gianotti-Crosti syndrome (GCS) is a self-remitting eruption related to viral infections. Ribavirin has been reported to be effective in treating severe GCS. Before clinical trials on antiviral agents, the magnitude of GCS affecting the quality of life in children should be ascertained. Aim: To investigate the impact of GCS on the QOL of children. Methods: Our setting was a teaching clinic. We validly translated the Children Dermatology Life Quality Index into Chinese. We recruited all children aged five to 16 years diagnosed with GCS over two years. For each child with GCS, we recruited the next age-and-sex pair-matched child consulting us for atopic dermatitis (AD), and the next age-and-sex pair-matched child brought to consult us for problems unrelated to the skin as controls. All study and control subjects completed the CDLQI. Results: 23 children were GCS and 46 children as controls were recruited. The impacts of GCS on children were significantly higher than children brought to consult us for problems unrelated to the skin (P < 0.05), with the parameters symptoms and feelings, leisure, school or holidays, and treatment mostly affected. However, the scores were low. Four (17%) study subjects and none (0%) in the second control had total CDLQI higher than 30%. The difference is insignificant (RR: inapplicable; P = 0.11). Impacts of AD on children were significantly higher than such for GCS (P < 0.001). Twelve (52%) children with AD and four (17%) children with GCS had total scores higher than 30% (RR: 3.00, 95% CI: 1.13 – 7.94; P < 0.05). When compared to a similar study on children with pityriasis rosea, the impacts of GCS were very similar to those of pityriasis rosea. Conclusion: GCS casts relatively low impacts on the QOL of children. These impacts were much lower than such of AD.
Authors and Affiliations
Antonio Chuh
Keywords
Related Articles
- EP ID EP328914
- DOI 10.9734/IJTDH/2016/25125
- Views 55
- Downloads 0
Pyo-adipocytolytic –Necrolysis Subcutis and Pan-necrotizing Subcutis: Unusual Dermato-Pathological Entities, Complications of Injection Abscess Given by Unskilled Personnels- Management and Outcome
Injection abscess are becoming common complications seen in sub-Saharan Africa. The abscess may further become a root for unusual dermato-pathological clinical findings when they are not initially managed...
Influence of Rheumatoid Factors and Bilirubin on the Sensitivity of Immunochromatographic Rapid Diagnostic Tests for HIV/AIDS and Hepatitis B in Cameroon
Aim: We aimed at studying the influence of some potential interference factors on the immunochromatographic Rapid Diagnostic Tests commonly used in Cameroon for the diagnosis of Human Immunodeficiency Virus / Acquired Im...
The Male: Female Ratio at Birth is Depressed by Maltese Parliamentary Elections and Increased by Other Non-electoral Events
Aim: The male to female ratio at birth declines with stress. In Malta, parliamentary elections are highly divisive and stressful. This paper looked at the association of M/F with parliamentary elections and other importa...
Parasitic Infestation in Cockroaches (Periplaneta americana) Obtained in Selected Areas of Metro Manila
Background: Cockroaches are insects recognized to be mechanical vectors of disease-causing agents but in the Philippines there is little information on what particular parasites inhabit these organisms. Objectives: This...
Radiological Features of Right Destroyed Lungs Syndrome with Pathologic Dextrocardia
Chronic lungs disease such as relapsed tuberculosis of the lungs could lead to complications that could alter the gross anatomy of a region of the body. Many complications have been reported due to chronic and relapsed l...