THE IMPORTANCE OF AXIAL TRIRADIUS ‘T’ IN PREDICTING TREATMENT RESPONSE IN SCHIZOPHRENIA PATIENTS RESISTANT TO CLOZAPINE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 38
Abstract
BACKGROUND Dermatoglyphics is being identified as an important diagnostic aid in a number of diseases having hereditary basis. Genetics play an important role in aetiology of Schizophrenia. A large number of schizophrenia patients are resistant to routine treatment with clonazepam. This resistance has been attributed to a further insult to the nervous system during its development from ‘neuroectoderm,’ which also gives rise to skin. Hence, any such resistance will be manifested more in the dermatoglyphic prints. MATERIALS AND METHODS This is a descriptive study. Study was done on 188 patients of schizophrenia of both sexes (144 treatment responders and 44 treatment non-responders). RESULTS Axial triradius t’ was the common position seen in the right hand of the female non-responders. Commonest position was t. The t’ position of the axial triradius is the most common position in both hands of male non-responders. CONCLUSION Amongst all other parameters axial triradius t’ stood out as a very important parameter to predict treatment resistance at an early stage. It was found to be significantly important from our study.
Authors and Affiliations
Aastha Aastha, Mathangi Santhosh Kumar
Keywords
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- EP ID EP548078
- DOI 10.14260/jemds/2018/937
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