THE IMPORTANCE OF C-REACTIVE PROTEIN IN DISCOGENIC LOW BACK PAIN: THE ANALYSIS OF 444 PATIENTS
Journal Title: Journal of Turkish Spinal Surgery - Year 2018, Vol 29, Issue 2
Abstract
Background: Low back complaint is the most common health problem. Recent studies point out the role of inflammation on discogenic back pain. In this study, we intended to examine the importance of C-reactive protein (CRP) level in discogenic low back pain. Material and Methods: 444 patients with discogenic low back pain were assessed in three groups. The first group (n=229) consisted of patients who appealed to outpatient clinic and who were recommended medical therapy. In the second group (n=15), there were patients who appealed to outpatient clinic and who were offered operation but who did not accept surgery. As for the third group (n=200) included patients who were operated because of single level lumbar discopathy. All patients were assessed in terms of CRP positivity at the first admission and whether surgery is recommended or not. Results: Positivity of CRP was significantly higher in the group to whom surgery is recommended (n=215) than in medical treatment recommended patients (17.8 % vs. 3.1 %, p < 0.0001, OR=6.8, 95 % CI: 2.9-15.6). Furthermore, the positivity of CRP was found significantly higher in the third group compared to the first group (18 % vs. 3.1 %, p < 0.0001, OR= 6.9, 95 % CI: 3.1-16.1). However, it was relatively higher in the second group than in the first group (13.3 % vs. 3.1 %, p=0.0626, OR=4.9, 95% CI: 0.9-25.9). Conclusion: Discogenic low back pain is caused by both mechanical and inflammatory factors. Preoperative CRP values can be predictive for inflammatory process in lomberdiscopathy. For more accurate results further studies are needed.
Authors and Affiliations
Emre DURDAG, Serdal ALBAYRAK, Ibrahim Burak ATCI, Soner CIVI, Ozgur KARDES, Süleyman Serdar KOCA
Keywords
Related Articles
- EP ID EP676999
- DOI -
- Views 132
- Downloads 0
SİDE - SHIFTING EXERCISES FOR THE TREATMENT OF ADOLESCENT IDIOPATHIC SCOLIOSIS
The pathogenesis of idiopathic scoliosis remains unknown despite extensive studies. Muscle dysfunction, skeletal factors, genetic facîors, metabolic and Chemical factors and abnormal function of the Central nervous Syste...
SYRINGOMYELIA
Objective: The cavities imbued with glia cells which may develop around the central canal of spinal cord are called syringomyelia. The pathophysiology of syringomyelia is yet to be defined in full. The aim of our stud...
RESULTS OF COMPLETE HEMIVERTEBRA EXCISION WITH A POSTERIOR APPROACH ALONE, FOLLOWED BY CIRCUMFERENTIAL FUSION AND POSTERIOR INSTRUMENTATION, IN PATIENTS WITH FULLY SEGMENTED AND UNINCARCERATED HEMIVERTEBRAE
Objective: To evaluate the results of surgical treatment of patients with an unincarcerated fully-segmented hemivertebra treated with hemivertebrectomy by a posterior approach alone, circumferential fusion and posteri...
TRANSPEDICULAR FIXATION IN FRACTURE-DISLOCATIONS OF THE CERVICAL SPINE: TWO YEARSʼ EXPERIENCE
Object: Transpedicular fixation technique, by means of anterior or posterior approaches, is known to be a biomechanically stronger method in cervical fracture-dislocation. Pedicle axis views are obtained using fluoros...
INTRAOPERATIVE AUTOLOGOUS BLOOD TRANSFUSİON İN SPINAL SURGERY
We evaluated the effectiveness of intraoperative autologous blood in reduction of the need for transfusion of ho-mologous blood in majör spinal surgery in two patient groups. İn Group A (30 patients) autologous blood and...