The Importance of Dietary and Lifestyle Changes in Health Improvement
Journal Title: Journal of Clinical Medical Research - Year 2024, Vol 5, Issue 2
Abstract
Nowadays, life expectancy has become a global phenomenon. Because of this, the concept of “Healthy Longevity” has attracted attention in recent years, as it encompasses not only living a long life but also living a life free from major chronic diseases such as DM2, hypertension and dyslipidemia. In this context, recent studies have demonstrated the significant impact of dietary changes and physical activity on healthy aging. First of all, nutrition is a key component affecting our health and several studies have shown that nutrition also has the potential to increase life expectancy. Calorie restriction without causing malnutrition has the power to reduce insulin and Insulin Growth Factor-1 (IGF-1) signaling, inhibit the mechanistic Target of Rapamycin (mTOR) signaling, activate AMP-Activated Protein Kinase (AMPK) and Sirtuin 1 (SIRT1), upregulate the NAD+ pathway and autophagy and reduce inflammation and oxidative stress. The Mediterranean diet, which includes an abundance of plant foods such as fruits, vegetables, whole grains, nuts and legumes; olive oil as the main source of dietary fat; fish and poultry consumed in low-to-moderate amounts; relatively low consumption of red meat; and moderate consumption of wine, is associated with lower rates of CVD and cancer. Higher intakes of unsaturated fats (found in plant-based foods and marine fish), particularly linoleic acid, exhibit the strongest inverse association with mortality. For individuals with lactose intolerance, opting for goat cheese is recommended. Additionally, eliminating the use of aluminum cookware and aluminum-containing deodorants and addressing vitamin deficiencies based on laboratory results, are also crucial.
Authors and Affiliations
Sandra Gordilho Tavares, Ruth Rosemberg Luz Cosmo Gomes
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