The influence of intravenous solution «Neoreodez» on the course of experimental endotoxemia and evaluation of the regenerative properties of drug in the conditions of application
Journal Title: Медичні перспективи - Year 2016, Vol 21, Issue 3
Abstract
In the experiment it was shown that experimental endotoxemia induced by introduction of carbon tetrachloride and bacterial lipopolysaccharide is characterized by activation of free radical oxidation and failure of antioxidant defense system. Intravenous injection of solution «Neoreodez» under these experimental conditions has a positive impact on the course of endogenous intoxication, which is manifested by decrease in the concentration of MDA and DC in the liver on average by 1Ѕ times (pd0.05), decrease in the level of AlAT and AsAT serum by 2 times (pd0.05) and to restore the balanced functioning of antiradical protection – increased activity of SOD by 1.6 times (p<0.05) in comparison with the performance of the active control. It is established that two-week application «Neoreodez» of solution potentiate the processes of natural reparation of damaged skin.
Authors and Affiliations
V. Mamchur, S. Dronov , G. Bilenkyi
Keywords
Related Articles
- EP ID EP123436
- DOI -
- Views 88
- Downloads 0
Remote clinical prognosis in patients with coronary X syndrome
The article analyzes data of 3234 coronary angiographies with established coronary X syndrome (CXS) in 217 cases, herewith expressed tortuosity of coronary arteries (ETCA) was found out in 148 (more than 2/3) of cases. A...
Мікробіологічний пейзаж слизових оболонок урогенітальних органів у жінок
В работе проведен детальный анализ состава микроорганизмов, которые могут контаминировать слизистые оболочки мочеполовой системы женщин в норме и при формировании определенных дисбиотических состояний. Состав микрооргани...
Role of biomarkers in diagnostics, stratification of risk and prognosis of heart failure
Heart failure occupies one of the leading places in the structure of the causes of adult mortality in the world. The issues of timely diagnosis and prognosis of the outcomes of this disease do not lose their relevance du...
Duodenogastral reflux and its influence on manifestation of morphological changes of gastric mucosa
Among the diseases of the gastroduodenal zone chronic gastritis (CG) occupies one of the leading positions. One of the main forms of CG is reflux gastritis (RG) based on long-term location of duodenal content in the gast...
Professor Beliayeva Nina Vasilievna (to 90-th birthday)
Professor Beliayeva Nina Vasilievna