The influence of selected clinical and morphological factors on treatment results of patients with advanced cancer of the larynx
Journal Title: Otolaryngologia Polska - Year 2013, Vol 67, Issue 1
Abstract
Introduction: The aim of the study was to indicate independent prognostic factors of treatment in group of patients with advanced cancer of the larynx. Material and method: The paper presents results of univariate and multivariate analysis of selected clinical and morphological factors in the group of 355 patients with advanced laryngeal cancer treated in the ENT Clinical Department in Zabrze in the following years 1998–2007. The analysis of the results of treatment in relation to clinical and morphological features of the tumor was based on overall survival, disease-free survival, local control and locoregional control. The results of analysis allowed to indicate the independent prognostic factors for outcome in patients with advanced laryngeal cancer. Results: Univariate analysis showed that the increase of clinical advancement of laryngeal cancer was associated with worse prognosis, as well as the fact that the primary location of the tumor in supraglottis and infiltration in laryngeal part of pharynx determined the worse outcome. Univariate and multivariate analysis confirmed that the number of lymph node metastases in the surgical specimen and microscopic radical of surgery were the most important prognostic factors for survival and cure in the study group. Conclusion: The strongest independent prognostic significance for all efficacy criteria have: completeness of operation and number of metastatic lymph nodes.
Authors and Affiliations
Katarzyna Miśkiewicz-Orczyk, Grzegorz Namysłowski, Maciej Misiołek, Wojciech Majewski
Impact of adenoid hypertrophy on the open bite in children
Nasal obstruction caused by adenoid hypertrophy can lead to malocclusion. The research material consisted of children aged 7–12 years with adenoid hypertrophy qualified for adenoidectomy. On the basis of the conducted te...
Burzliwa historia operacji ucha środkowego
The paper is a review of primary and secondary historical and scientific literature concerning the surgical treatment of the middle ear diseases. The development of mastoid surgery can be traced through the past 4 centur...
Powikłania ogólne operacji nowotworów złośliwych głowy i szyi
Każda procedura zabiegowa niesie ze sobą ryzyko powikłań zarówno miejscowych, związanych z typem operacji, jak i ogólnych, a ich wystąpienie zależy od wielu czynników leżących po stronie pacjenta, jaki po stronie zespołu...
Test eferentny ślimaka – czułość i swoistość metody
Introduction. The amplitude of click evoked otoacoustic emissions can be suppressed (reduced) with contralateral acoustic stimulation (CAS). This is thought to be due to the inhibitory control that the medial efferent au...
Małoinwazyjna rynoplastyka z użyciem kwasu hialuronowego i toksyny botulinowej u 49-Ietniej kobiety
SUMMARY A significant component of human appearance and a major aspect of one's profile depend on the shape of the nose. This shape can be distorted by a variety of factors. To date, treatment options reported have inclu...