THE INVESTIGATION BY DOPPLER ULTRASONOGRAPY OF BLOOD FLOW DYNAMICS OF TESTES AND LIVER IN MEN EXPOSED CHRONICALLY TO TOLUENE
Journal Title: Journal of International Dental and Medical Research - Year 2010, Vol 3, Issue 2
Abstract
Organic solvents used in various industrial processes may cause toxic effects in various biological tissues of human. Many previous studies have demonstrated, histopathologically, that toluene produced toxic effects in liver and testes. The aim of this study was to investigate the arterial and venous blood flow rate in the liver and testes of male workers who experienced occupational exposure to toluene. The experimental group comprised 30 male painters who had experienced occupational exposure to toluene inhalation for a minimum of 10 years; a control group comprised 30 healthy, age-matched male volunteers. The blood flow rate of the testes and liver of both groups were determined by Doppler ultrasonography. We determined that some arterial and venous blood flow rates of liver and testes changed in painters exposed occupationally to toluene (p<0.05). The results indicated significant changes in arterial and venous blood flow rate of right testes, left testes arterial end diastolic flow, left testes arterial flow and main hepatic venous blood flow rate of the right lobe of the liver. Other parameters showed no statistically significant difference. We conclude that long-term occupational exposure to toluene can affect arterial and venous blood flow. The results indicate testes and liver tissue damage in these subjects.
Authors and Affiliations
Cemil Sert, Ocal Sirmatel, Erkan Yildiz, Ferat Oruc
Keywords
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