THE LEVEL OF CYTOKINES IN PATIENTS WITH CHRONIC VIRAL HEPATITIS C, DEPENDING ON THE IL-28B GENOTYPES
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2018, Vol 5, Issue 11
Abstract
The imbalance in the of cytokines plays a pivotal role in pathogenesis of various diseases, and chronic viral hepatitis C is not an exception. Various cytokines, namely IL-2, IL-4, IL-6, TNF-α, IFN-α and IFN-γ, are studied in chronic viral hepatitis C patients in accordance to their IL-28B gene polymorphisms. Obtained data showed reliable differences between polymorphisms, thus these cytokines profiles can be used to elucidate pathology of CHVC and help in development of novel diagnostic tools.
Authors and Affiliations
Rozumbetov R. J.
Keywords
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